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Cycloblastin (Cyclophosphamide)

Cycloblastin is a drug that is used primarily for treating several types of cancer. In order to work, Cycloblastin first is converted by the liver into two chemicals, acrolein and phosphoramide. Acrolein and phosphoramide are the active compounds, and they slow the growth of cancer cells by interfering with the actions of deoxyribonucleic acid (DNA) within the cancerous cells. Unfortunately, normal cells also are affected, and this results in serious side effects. In addition to slowing the growth of cancerous cells, Cycloblastin also suppresses the immune system and is referred to as immunosuppressive. The FDA approved Cycloblastin in November 1959.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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Identification of some benproperine metabolites in humans and investigation of their antitussive effect. Structural identification of a new tri-p-coumaroylspermidine with serotonin transporter inhibition from safflower. Repeat angiography some days later, when the vascular spasm had cleared, was likewise negative. A phase I dose-escalation trial of 2-deoxy-D-glucose alone or combined with docetaxel in patients with advanced solid tumors.

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The DNA methylation imprint is resistant to a genome-wide demethylation process in early embryos and is stably maintained in postimplantation embryos. Unusual presentations of Haemophilus influenzae infections in immunocompromised patients. Rehabilitation facilities for persons with hearing and speech problems. By using a technique based on sequence alignments and the known structure of the a and b domains of human PDI, we generated a large number of domain constructs for all six redox-active human PDIs: PDI, PDIp, ERp72, ERp57, P5, and PDIr.

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Induction of isoacceptor tRNAs during the secretion of fibroin in the silkgland of Bombyx mori L. This information is important for identifying new therapeutic targets that may be relevant in treating diseases that involve the BAFF/APRIL cytokine network.

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Functional relevance of microbiome signatures: The correlation era requires tools for consolidation. As part of the government response to the Deepwater Horizon blowout, a Well Integrity Team evaluated the geologic hazards of shutting in the Macondo Well at the seafloor and determined the conditions under which it could safely be undertaken. Genetic encoding of DNA nanostructures and their self-assembly in living bacteria.

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Electrostatics-Driven Hierarchical Buckling of Charged Flexible Ribbons. Of particular concern in 25-gauge surgery is the increased risk of associated endophthalmitis. However, effective pain management is dependent upon valid and reliable pain assessment. Effects of perfluorocarboxylic acids on the activities of acyl-CoA elongations in vivo and in vitro. The combination of quinazoline and chalcone moieties leads to novel potent heterodimeric modulators of breast cancer resistance protein (BCRP/ABCG2).

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Congenital atresia and agenesis of lacrimal ducts: clinical aspects, diagnosis, treatment Primary outcomes were vital status and renal function at hospital discharge and at 5 and 10 years of follow-up. A combination of these categorisations provides 5 groups with significantly different levels of PM10, improving the discrimination of the conventional classification.

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Choosing the best ancestral character state reconstruction method. Calcium-enriched foods and bone mass growth in prepubertal girls: a randomized, double-blind, placebo-controlled trial. This case illustrates that clinicians should base their decision on whether to perform surgery on clinical manifestations, imaging findings, and cytology of mucin obtained by drainage when it is difficult ilacabak augmentin suspension to obtain malignant cells by biopsy.

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Rho GTPases regulate the tethering of exocytic vesicles and modulate their subsequent fusion. Effects of low and high doses of gemifloxacin e levofloxacin 750 mg selective sigma ligands: further evidence suggesting the existence of different subtypes of sigma receptors. Adhesion of Streptococcus mitis and Actinomyces oris in co-culture to machined and anodized titanium surfaces as affected by atmosphere and pH. Carbon kinetics of milk formation in Holstein cows in late lactation.

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