Levothroid - drug, sodium salt of L-thyroxine. After partial metabolism in the liver and kidneys, it affects the development and growth of tissues and metabolism. The levorotatory isomer of thyroxin, after partial metabolism in the liver and kidneys, has an influence on the development and growth of tissues and metabolism. Mechanisms of metabolic effects include receptor binding to the genome, changes in oxidative metabolism in mitochondria, as well as regulation of the flow of substrates and cations outside and inside the cell. In small doses, has an anabolic effect. In medium doses, it stimulates growth and development, increases tissue oxygen demand, stimulates the metabolism of proteins, fats and carbohydrates, and increases the functional activity of the cardiovascular system and the central nervous system. In large doses, inhibits the production of thyrotropin-releasing hormone hypothalamus and thyroid-stimulating hormone of the pituitary gland. The therapeutic effect is observed after 7-12 days, during the same time the effect is preserved after drug withdrawal. The clinical effect of hypothyroidism appears after 3-5 days. Diffuse goiter decreases or disappears within 3-6 months, with late nodal stages, a significant reduction in the size of the thyroid gland is observed in 30% of cases, but almost all patients are warned of its further growth.
Other names for this medication:
Levothroid,
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