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Copper(II) carboxylate-promoted intramolecular carboamination of alkenes for the synthesis of polycyclic lactams. Criteria for the diagnosis of heat-related deaths: National Association of Medical Examiners. The method was confirmed to be of sufficient sensitivity and reliability to use as a diagnostic assay.

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Problems were centrally coded, using the International Classification of Primary Care (ICPC). We concluded that alpha-TCP should be mixed with calcium and phosphate solutions since this results in a moderate setting time and fast transformation to HAP even if the method of mixing becomes a little complex.

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Acute cerebellar ataxia and hearing loss as initial symptoms of infectious mononucleosis. Longer-term follow-up is needed to determine the long-term stability of aneurysmal occlusion. The SPG has been a therapeutic target to treat primary headache disorders for over 100 years. We studied 1,143 women with breast cancer who had completed BRCA1 and BRCA2 mutation screening as a result of a high risk for hereditary breast cancer.

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We review recent advances in modelling the gene-protein interaction networks that control circadian rhythms, cell cycle progression, signal processing and the design of synthetic gene networks. We speculate that any drastic changes in neurogenesis will negatively impact the hippocampal memory processing. The frequently stress responsive and diverse expression profiles of the GsTIFY gene family suggests that this family may play important roles in plant environmental stress responses and adaptation.

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The reactivity of the N-bonded and C-bonded aryl groups in the tzNHC ligand was found to be significantly different with respect to intramolecular aromatic C-H bond activation. nAChR modulators also influence neural processes that appear to mediate the behavioral effects of antidepressants, such as hippocampal cell proliferation.

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First, we titrated the photovoltaic interface and electrolyte with TBP to identify the stepwise chemical interaction processes. Infection site concentrations: their therapeutic importance and the macrolide and macrolide-like class of antibiotics.

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Developmental anatomy of the reproductive shoot in Hydrobryum japonicum (Podostemaceae). From October 1998 to December 2000, 162 couples were enrolled, and ICSI and PTSA were adopted.

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Thus, as with the pituitary receptor, this placental receptor transcript appears to encode a single polypeptide chain with seven intramembranous domains and two glycosylation sites. Multiple studies have confirmed the presence of HBoV in respiratory tract samples of children world-wide. Depressive disorders in elderly and senile patients in the period of rehabilitation after acute ischemic stroke Testing seven breast cancer-associated genes, followed by risk-reduction management, could cost-effectively improve life expectancy for women at risk of hereditary breast cancer. We have identified a strong candidate gene for hbd, Sec15l1, a homologue to yeast SEC15, which encodes a key protein in vesicle docking.

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The expression of this molecule is completely abolished in the lymphoepithelial regions of the crypt epithelium. A case of avoidable heterotopic pregnancy after single embryo transfer. Twenty-one thousand five hundred twenty-six older adults (13,760 women, 7,766 men) with dementia newly started on oral atypical antipsychotic therapy between April 1, 2007, and March 1, 2010. Acrolein-induced toxicity--defective mitochondrial function as a possible mechanism. Indoor environment of the hospital was contaminated with airborne microbiotas, which are common cause of post-surgical site infection in the study area.

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These immune-inflammatory profiles develop as a consequence of a functional impairment of T regulatory (Treg) lymphocytes, which promotes the activation of dendritic cells directing the differentiation of distinct Th cell subsets. The present study can be translated to the clinic by various effective methods of fluorescently labeling tumors. In both HepG2 and HH01 cells, PMA treatment induced a rapid morphological change with characteristics of cytoskeletal reorganization.

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Obstetric management in the presence of an omphalocele should therefore include immediate amniocentesis for chromosomal analysis and ultrasonic scanning of the fetus for other structural abnormalities. We highlight that artefact signals from co-sampled pollutants such as CO2 can be greater than the electrochemical sensor signal generated by the measurand. Efforts to develop a Quality Assurance Program at the Joint Center for Radiation Therapy will be described.

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This may lead to a lower chance of a spontaneous vaginal birth and a higher risk on a PPH. One patient who ingested 60 mg of alprazolam had clinically significant respiratory depression in the emergency room but recovered fully within 24 hours. Inhibitory effects of ellagic acid on the direct-acting mutagenicity of aflatoxin B1 in the Salmonella microsuspension assay.

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Comparison of hypospadiac and normal preputial vascular anatomy. Considering the amazing organization shown by the acrosome of some urodele amphibians, HPA-colloidal gold cytochemistry was used to analyze the biogenesis of the acrosome in the urodele Pleurodeles waltl at electron microscopy level. Occupational exposure to cobalt is of widespread concern due to its use in a variety of industrial processes and the occurrence of occupational disease.

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This cross-sectional study was conducted at Riyadh Military Hospital, Saudi Arabia, on a convenience sample of adult Saudis attending its clinics. Examining the factor structure of the 39-item and 15-item versions of the Five Facet Mindfulness Questionnaire before and after mindfulness-based cognitive therapy for people with recurrent depression. Simultaneous ureteral and bladder substitution is one of the most challenging and traumatic surgical interventions.

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Abdominal surgery can be safely performed using RA alone in selected high-risk patients, making this option an attractive alternative to GA for those with severe pulmonary impairment. Effect of hyperbilirubinemia on biologic rhythms in healthy full-term neonates Metformin had no significant effect on either peripheral glucose clearance or the rate of glucose oxidation. Macronuclear Actin copy number variations in single cells of different Pseudokeronopsis (Alveolata, Ciliophora) populations. However, when TNF-alpha antiserum was applied 1 h after injury and NOS antiserum was given either before or after TNF-alpha antiserum, no neuroprotective effects were observed.

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To determine the effect of stress on the masticatory muscles function in young healthy adults. After first-strand cDNA synthesis, mRNA induction was measured, using a polymerase chain reaction (PCR) technique for COX-2, iNOS, and glyceraldehyde 3-phosphate dehydrogenase.

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Here, we describe the discovery of miravirsen, which is currently in phase 2 clinical trials for treatment of hepatitis C virus (HCV) infection. Use of erythrocytes for evaluating the action of chemical compounds on the body of workers After 16 and 31 weeks the pulmonary arterial pressure dropped significantly from the baseline value of 88 mm Hg to 63 and 58 mm Hg, respectively. A role for inducible nitric oxide synthase (iNOS) was recently proposed. We describe a simple method of removal that is comparable to its importance.

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In addition, quercetin glucuronide-induced apoptosis was totally blocked by the broad-spectrum caspase inhibitor benzyloxycarbonyl-Val-Ala-Asp fluoromethylketone. Risk stratification revealed that HPV DNA testing was not beneficial for HSIL cases, whereas it was for ASCUS and, in some combinations, for negative and LSIL cytology. ActRIA (or ALK2), one of the type I receptors of the transforming growth factor-beta (TGF-beta) superfamily, can bind both activin and bone morphogenetic proteins (BMPs) in conjunction with the activin and BMP type II receptors, respectively. Three patients experienced postoperative CSF leaks: 1 with ePTFE dural substitute and 2 without. We reviewed the literature and gathered information, although sparse, to propose guidelines for using these drugs in renal insufficiency patients.

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Modic changes of the cervical spine in patients with whiplash injury: a prospective 11-year follow-up study. Forty-one next of kin who had served as primary surrogate decision makers before the death of their loved one in the intensive care unit 3-12 months previously. Effect of muscle temperature on rate of oxygen uptake during exercise in humans at different contraction frequencies.

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The vessels of injury included the common carotid artery, subclavian artery and accompanying veins. Microarray method to monitor 40 intestinal bacterial species in the study of azo dye reduction.

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Supplemental CrProp administered at 10- and 50-fold doses of the basal dietary Cr level has a significant antidiabetic effect in insulin resistant rats. MID severity patients in both programs showed the most dramatic effects of treatment duration, with generally large improvements in all criteria at greater treatment lengths. Retrospective evaluation of consecutive 275 patients affected by LACC (IB2-IIB), undergoing NACT followed by type C/class III radical hysterectomy.

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The authors have developed a brief rating scale to expedite the rapid screening of emergency psychiatric patients who require hospital admission from those who are suitable for outpatient crisis intervention treatment. Oxidation-reduction properties of chloroplast thioredoxins, ferredoxin:thioredoxin reductase, and thioredoxin f-regulated enzymes. Wild-type ebg beta-galactosidase, encoded by ebgA, is a catalytically feeble enzyme that does not hydrolyze lactose or other beta-galactosidase efficiently enough to permit growth on those substrates. A mysterious disease spread over Cuba from 1991 to 1993, the cause of which has not been fully established. Inappropriate device discharges, a frequently reported AICD-associated complication, are discussed.

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The Danish Allergy Research Center (DARC) cohort encompasses 562 infants invited to a clinical examination including patch tests with nickel sulfate six times during the first 36 months of life. Functional neuroimaging may cast further light on the neurobiology of specific language impairment and serve as a means of developing and evaluating therapy.

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In the two patients tested, donor DNA was not detected by polymerase chain reaction, suggesting the absence of microchimerism. These complexes are of inherent interest for their dynamic stereochemical properties, but may also find use in optical display technology, data storage, telecommunications, or electromechanical devices. A central or peripheral neurogenic lesion is frequently found to be accounting for the problem.

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The role of myocardial dysfunction remains to be defined as there was no correlation with clinical severity. Treatment with norcantharidin of colorectal cancer cells not only inhibited cell proliferation, but also induced apoptosis.

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The effects of optic nerve transection on optic axon and retinal cell survival was studied in C57BL/6J mice. Dietary data were collected using the weekly food frequency questionnaire and the 24-hour dietary recall method, while state and trait anxiety was assessed through the use of the Spielberger State-Trait Anxiety Inventory (STAI) and the Zung anxiety scale. Substantial progress has been achieved in recent years in the field of cancer immunotherapy, with various strategies employed to elicit a host immune response against the tumor.

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Generally, most or all of this increase can be attributed to second-generation antipsychotics (SGAs). The DGGE profiles of the domain Archaea and the three orders Methanosarcinales, Methanomicrobiales, and Methanobacteriales were comparatively analyzed after each DGGE band was sequenced to enable identification. The United States is the most productive country in the subspecialty critical care medicine. Until recently, cytokine therapy has been the only validated option for patients with advanced renal cancer. Children were allocated at random to the intervention or the control group before any contact with the parents was made.

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Two different nucleases were employed, showing the versatility of this assay for multiple turnover label-free nuclease studies. aureus isolated from burn wound infections in Yekatit 12 Hospital, Addis Ababa Ethiopia. Rosuvastatin decreased the viability of the human umbilical endothelial cells (HUVECs) (one-half inhibitory concentration: 5.87 microM) by inducing G(1) phase arrest and promoting apoptosis.

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We argue that some MUP structural genes are quite actively transcribed in females and that the transcription of others is dependent to different degrees upon induction by testosterone. The mental health of children is too frequently overlooked in resource scarce low and middle-income countries. pH-dependent binding modes observed in trypsin crystals: lessons for structure-based drug design. New substances involved in iron metabolism continue to be described. This effect was found to be both transient and fully reversible, with the microtubule arrays reforming after further incubation.

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The utility of ETA blockers has been greatly limited, however, by fluid retention, sometimes leading to heart failure or death. The isolated fracture of the anterior inferior iliac spine (generalities and contribution of 3 cases)

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Identification of angiotensin II-binding domains in the rat AT2 receptor with photolabile angiotensin analogs. We previously reported that STAT1 expression was significantly downregulated in Gata1-knockdown murine megakaryocytes, which also have impaired terminal maturation.

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The entire lesion was removed in one session with no complications. The value of computed tomography angiography in determining treatment allocation for aneurysmal subarachnoid hemorrhage. It should include a cycloplegic refraction to rule out excessive farsightedness, nearsightedness, astigmatism or unequal refraction in the two eyes.

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All but one showed tissue specificity of expression: one was expressed in stomach and small intestine and three were in placenta. In a subsequent efficacy study, changes in vascular function in 41 medicated diabetic patients were assessed after a 30-day, thrice-daily dietary intervention with either flavanol-rich cocoa (321 mg flavanols per dose) or a nutrient-matched control (25 mg flavanols per dose). The tract neurones were monosynaptically activated by afferents in the ipsilateral forelimb and projected to the same area of the LRN. Injectable microcapsules prepared with biodegradable poly(alpha-hydroxy) acids for prolonged release of drugs. There were no significant changes in heart rate and blood pressure in all experimental groups.

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A 3-year-old Collie bitch was euthanatized two weeks after the onset of blindness and deafness. The amount of toxicity manifested by patients receiving PRM as their initial antiepileptic drug was not different from that of those patients previously treated with phenytoin (PHT) or carbamazepine (CBZ).

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In rural areas with limited health care resources, screening by visual oral examination involving minimum cost may prove useful to reduce oral cancer mortality. With a contribution to the problem of intratracheal or intraperitoneal dust testing

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Bone metastases are critical lesions greatly impairing the quality of patients with malignancies. HLA plays a critical role in HSCT, but its involvement in HSCT is constantly in flux because of changing technologies and variations in clinical transplantation results. We showed that expression of both type IV collagenases was remarkably higher in carcinoma samples than in lung parenchyma. The administration of K252a, an inhibitor of BDNF receptor, significantly reduced cell proliferation in the subgranular zone of dentate gyrus.

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Bioactivity guided fractionation and hypolipidemic property of a novel HMG-CoA reductase inhibitor from Ficus virens Ait. These findings suggest no differences between asymptomatic and symptomatic individuals, but differences may exist between concentric and eccentric VMO/VL ratios. ERK pathway mediates the activation of Cdk2 in IGF-1-induced proliferation of human osteosarcoma MG-63 cells. Radiologist reader performance for breast cancer detection using mammography plus automated whole-breast ultrasound (AWBU) was compared with mammography alone. GCS with lighter pressures may be more suitable for subjects whose daily work requires long-term inactive standing or sitting, and GCS with mild pressure appear to be sufficient for most clinical applications.

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First-year medical students were more likely than fourth-year students, and fourth-year students more likely than physicians, to perceive unfair treatment. Critical micelle concentrations (CMCs) of three ionic surfactants that contain n-decyltrimethylammonium ion as a surfactant cation and bromide, perfluoroacetate, and perfluoropropionate anions as a counterion, respectively, were determined by electrical conductivity at several temperatures. Serum level of sICAM-1 was determined in 13 patients with acute hepatic A, 19 patients with acute hepatitis B, and 20 healthy controls. The morphometric measurements indicate earlier onset of atrophic changes in ectopic pregnancy.

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Often situated in large apartments in mostly urban settings, SHA are a specific German kind of small-scale living facilities for older care-dependent persons, predominantly suffering from dementia. This study did not show significant differences between the classes in preventing renal function decline in DM2 patients in primary care. One-and-a-half syndrome: a less appreciated emergency in native valve infective endocarditis.

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Fusiform aneurysms involving the A2 or distal A1-A2 segment of the anterior cerebral artery are uncommon and difficult to manage surgically with simple coiling or clipping. Populus euphratica HSF binds the promoter of WRKY1 to enhance salt tolerance.

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Use of muscle pedicle flaps for failed bladder neck closure in the exstrophy spectrum. Hence, it appears that round spermatids express the precursor forms of the NGF gene product, but not the mature form of NGF beta, and that the NGF beta moiety of the NGF precursor proteins exhibits trophic activity in the rescue of Sertoli cell viability, consistent with the paracrine regulation of spermatogenesis.

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To understand the population evolution of this rust fungus will facilitate the control of this disease and the breeding of rust-resistant wheat. In CHF patients with renal dysfunction EMD 87 580, clearance is reduced and plasma concentrations increased.