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In a limited number of recent studies, stress-induced premature cellular senescence in this biologically aged population also was described. The present study assessed the association between serum 24S-hydroxycholesterol (24S-OH-Chol) and 27-hydroxycholesterol (27-OH-Chol) and hippocampal volumes in 69 middle-aged cognitively normal individuals. Studies were included if they were randomised controlled trials which compared lactulose with polyethylene glycol in the management of chronic constipation. Hereditary neuropathy with liability to pressure palsy in patients under 30 years old: Neurophysiological data and proposed electrodiagnostic criteria.

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Focal grey matter atrophy within the motor homunculus corresponds with functional disability in ALS. The data collected included date of fracture, age, gender, type of fracture, and injured teeth. No comparable accumulations of Tc-99m activity were noted in normal subjects or in a subject with heterozygous familial hypercholesterolemia who had very small tendon xanthomas. In this regard, a full understanding of gas exchange mechanism in ARDS is imperative for individualized symptomatic support of patients with ARDS. The lignin concentration was reduced in the supernatant, while the sugar content remained unchanged.

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Isolation, screening nd characterization of hydrogen-oxidizing bacteria in soybean rhizosphere Functional links between canine height and jaw gape in catarrhines with special reference to early hominins. A case of paraganglioma of urinary bladder in a 96-year-old female When coadministered with EE, ICI 182780 inhibited the cholesterol-lowering and uterotropic activities of EE, suggesting that the estrogen receptor pathway is involved.

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Isolation and characterization of a novel Forssman active acidic glycosphingolipid with branched isoglobo-, ganglio-, and neolacto-series hybrid sugar chains. The measurements were performed with picosecond pulses at 532 nm in Fe(III)-meso-tetrakis(4-N-methyl-pyridyl) porphyrin.

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ROC curves showed that the PAR index had an acceptable level of validity with the professional assessment of orthodontic treatment need in Asian malocclusions. The results of this study will provide feasibility and preliminary data prior to the construction of a larger, multicentre study. A single intraoperative bolus of intravenous methadone appeared to provide effective analgesia with an acceptable side-effect profile.

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The MOD group was fed with the AIN-76A diet (phytate undetectable) enriched with MgO, inositol and CaHPO4. Ductal carcinoma in situ that involves sclerosing adenosis: high frequency of bilateral breast cancer occurrence. Our findings of specific developmental patterns of expression and the correlation between immune targeting of the Hu proteins and adult neurodegenerative disease suggest that the Hu proteins are critical in both the proper development and function of mature neurons.

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Seventy-three cases of KOA were treated with the conventional acupuncture therapy at Liang-qiu (ST 34), Dubi (ST 35), Zusanli (ST 36), Yanglingquan (GB 34), Yinlingquan (SP 9), etc. The principle of regional perfusion using cytostatic drugs injected into the regional arterial blood flow resulted from a study by Klopp et al. Therefore, drought-induced perturbations in AA and ROS metabolism could potentially contribute to the observed enhanced susceptibility.

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typhimurium, mice lacking both NLRs were markedly more susceptible to infection. Supplemented eggshell restores calcium transport in chorioallantoic membrane of cultured shell-less chick embryos.

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We sought to assess the efficacy and complications of linear accelerator-based stereotactic radiosurgery (SRS) plus intracavitary irradiation (ICI) as salvage treatment for local persistent and recurrent nasopharyngeal carcinoma (NPC) after primary external beam radiotherapy (EBRT). It is uncertain to what extent high C-reactive protein (CRP) concentrations reflect the presence of inflammatory conditions in the community.

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It can be assumed that the effectiveness of the new agents is not only due to the low rate of hydrolysis, but also to the rapid binding to the lethal target. The intervention was implemented by one teacher with three classes of students, and the dependent variable was the percentage of students ready to begin class at the appropriate time. PET may obviate the need for depth electrode study in some patients with intractable partial seizures. The following results were obtained: Significant age-related changes were observed in the skin blood flow of the deltoid region, anterior chest, dorsum of the hand, and dorsum of the foot.

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The mechanism underlying Smurf2-mediated morphological changes during embryonic development may provide new mechanistic insights and potential targets for prevention and treatment of human osteoarthritis. Evidence indicates that this apparent lower availability of salicylate from SSA is due to incomplete hydrolysis to salicylic acid, the unhydrolyzed SSA being excreted mainly as glucuronide conjugates.

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IQ in late adolescence/early adulthood, risk factors in middle-age and later coronary heart disease mortality in men: the Vietnam Experience Study. The technique is based on the hybridization of labeled probes to complementary sequences in the DNA or RNA of the cells.

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The predicted Sas10p was 70,200 kD and strikingly rich in charged amino acids. Despite these developments, treatment of PFCs, and infected WON in particular, continues to be associated with significant morbidity and mortality. Internal hernias occur frequently after laparoscopic gastric bypass. The Fanconi anemia (FA) pathway can repair this type of DNA lesion, ensuring genomic stability. Multiple chronic conditions and low skeletal muscle mass are common features of aging that are detrimental to physical performance.

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In the SCD patients the frequency of single alpha-gene deletion (-alpha/alpha alpha) was 0.346, compared to 0.263 in the Hb AA group. Marked fibrinolysis and fibrinogenelysis as possible pathogenetic consequences of immunitary phenomena in the organism A patient in atrial fibrillation was referred for mitral valve replacement due to severe mitral regurgitation. Some urgent tasks in microbiology instruction in medical schools

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Rehabilitation of the ocular surface may be followed, if necessary, by standard penetrating keratoplasty if all aspects of ocular surface rehabilitation are complete, or by large diameter penetrating keratoplasty if successful limbal stem cell transplantation cannot be achieved but other ocular surface rehabilitation is complete. The buccopharyngeal and esophageal phases of swallowing are controlled by distinct networks of premotor neurons localized in the nucleus tractus solitarius.

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Evaluation of a new method for the preparation of homogeneous mycelial suspensions. These findings indicate that personality is important for change in physical activity, but physical activity is relatively unimportant for change in personality. Influence of purines on pyrimidine metabolism in rat hepatocytes. Prolonged access to the venous system using the Hickman right atrial catheter.

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In contrast, IFN-gamma was fully capable of inducing cytotoxic pM phi in the presence of Cy. The use of it does not always prevent seroma formation, but it can reduce drainage magnitude and duration, as well as decrease the incidence of seroma after the removal of drainage.

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Follow-up data of such patients using autofluorescence bronchoscopy proved that CIS regresses without further treatment in significant number of patients. Thermodilution cardiac output during haemodialysis: what are we measuring?

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Three 90-minute focus group discussions exploring breast cancer beliefs, attitudes, and practices were audiotaped, transcribed verbatim, and analyzed using thematic context analysis techniques. An autopsy case of acute carbon monoxide poisoning after a long-term vegetative state. Personality pathology and alcohol dependence at midlife in a community sample. Otosclerosis--an inflammatory disease of the otic capsule of viral aetiology? We also demonstrate that following stimulation, an underphosphorylated nondegradable form of IkappaBbeta accumulates.

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These results imply that genetic risk assessment for HSCT in Latin America has to be adapted for different population subgroups rather than as a pan-Hispanic/Latino analysis. Curcumin Upregulates Antioxidant Defense, Lon Protease, and Heat-Shock Protein 70 Under Hyperglycemic Conditions in Human Hepatoma Cells. We conclude that successful surgical management requires (1) suspicion of ventricular rupture, (2) hemodynamic stabilization by counterpulsation, (3) coronary arteriography, and (4) combined infarctectomy and repair with revascularization. Endothelial infection has an important role in the pathogenesis of Crimean-Congo hemorrhagic fever (CCHF).

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Optogenetic methodology enables direct targeting of specific neural circuit elements for inhibition or excitation while spanning timescales from the acute (milliseconds) to the chronic (many days or more). This method dose not require the inhalation of hydrogen gas which is necessary for the hydrogen gas clearance method and which is possibly harmful to humans.

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The forensic issue is therefore not whether nocturnal oviposition occurs, but rather whether the conditions of a particular case are more or less conducive to it. High-dose prescription of anticholinesterase and the advanced stage by Myasthenia Gravis Foundation of America (MGFA) classification have higher risks of postoperative crisis. These findings suggest that the neural networks and/or the neurotransmitters that subserve the propagation of pilocarpine and maximal electroshock seizures differ with regard to the entopeduncular nucleus. Therefore, it is logical to suggest that activation of PPAR-gamma may partially reverse the state of insulin resistance. Global analyses of Chromosome 17 and 18 genes of lung telocytes compared with mesenchymal stem cells, fibroblasts, alveolar type II cells, airway epithelial cells, and lymphocytes.

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Gluteal compartment syndrome following drug-induced immobilization: a case report. TAF-I has been shown to have significant amino acid similarity to nucleosome assembly protein-I (NAP-I), which is involved in the formation of the chromatin structure. Hydrogen-rich saline improved nitric oxide synthase activity, and malondialdehyde, nitrite and nitrate, and 8-hydroxydeoxyguanosine levels in the diabetic rat corpus cavernosum. It is particularly referred to the dangers of a too schematic approach.

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An asymmetric barrier to the spread of the neutral alleles exists on the two sides of the physical barrier, given the presence of symmetric barrier to the spread of the selective alleles. We found in the present study that IL-4 was highly expressed at 24 hr after contusive SCI in rats and declined thereafter, with concurrent up-regulation of IL-4 receptor subunit IL-4alpha.

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Relational issues such as familiarity or a desire to communicate trust were central in the explanations of condom non-use. Ecosystem health can be defined by requirements such as resilience, vigor, organization, and relations, which may be used for totally different systems as well. All subjects completed a behavioral gap detection procedure to establish their behavioral gap detection threshold (BGDT).

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Their bioactivity stems from enzymatic metabolic activation to reactive and highly electrophilic intermediates. Supplementation with tocotrienol-rich fraction alters the plasma levels of Apolipoprotein A-I precursor, Apolipoprotein E precursor, and C-reactive protein precursor from young and old individuals. The results apply only to situations in which there is no plugging of pores. The associations of birth size, rate of growth during infancy, and odds of childhood overweight have not yet been thoroughly investigated in contemporary cohorts in low- and middle-income countries. The objective of this study was to determine the different vascularization patterns of the posterior interventricular sulcus (PIS) with coronary CT angiography.

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A procedure for adsorbing virus neutralizing antibodies on paper disks. The present study was aimed at developing novel, selective, and potent GABABR PAMs with efficacy on abuse-related effects of nicotine. This method is of importance to doctors working single-handed in district hospitals in this country. The ability to sense and respond appropriately to environmental changes is a primary requirement of all living organisms. Cigarette smoking among pregnant women diagnosed with substance use disorders (SUD) is four times higher than smoking among pregnant women without SUD.

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Studies on the agglutination reaction of Mycobacterium tuberculosis Scanning electron microscopy has shown maturation of the epithelium although there has been some slowing or arrest of the process at the stage of immature squamous epithelium. Based on these results, it is recommended that kidney and liver transplants be offered to Danish HIV patients based on the same criteria as those that apply for non-HIV-infected patients with end-stage kidney or liver disease. Chemosensitivity testing of human neoplasms using the soft agar colony assay. Charge substitutions were also engineered to generate K12L and H27K nisin A variants, both of which were similar to I30W nisin A with respect to an overall reduction in phospholipid mobility.

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The high-purity preS1(21-119aa) coated antigen was successfully prepared by gene expression and affinity chromatography. Referential delusions of communication and interpretations of gestures. The objective was to investigate acoustic cue processing in lexical-tone recognition by pediatric cochlear-implant (CI) recipients who are native Mandarin speakers. This module biomarker is enriched with known causal genes and related functions of T2DM.

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To identify under-five-year-old children with vision or ocular defect in two provinces (Wilayats) of central Oman in 2006. Transmembrane calcium movements mediated by ionomycin and phosphatidate in liposomes with Fura 2 entrapped.

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Two groups of listeners were recruited to evaluate gender and provide masculinity and femininity ratings. This technique, however, differs from the direct sequencing of amplified DNA in that non-specific substitutions will render a molecule useless in analysis. Furthermore, oligomerization of the isolated carboxyl-terminal peptide binding domain is, like that of the entire protein, reversed by peptide binding, indicating that self-association of the protein may be mediated by the peptide binding site and, as such, should play a role in the regulation of HSC70 chaperone function.

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The maximum differences were 0.36mm in 4D PET/CTand 0.57mm in CTs in the antero-posterior axis. The mechanical microconnector system (mMS) is a multi-channel system composed of polymethylmethacrylate (PMMA) with an outlet tubing system to apply negative pressure to the mMS lumen thus pulling the spinal cord stumps into the honeycomb-structured holes. Recent seminal discoveries guiding the future include selective elicitation of both Type 1 and Type 2 immune responses, and prime-boosting using recombinant viral or DNA vectors and expressed antigens. This was a longitudinal, before/after study in five emergency departments (EDs) in a healthcare system with a common electronic health record.

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Participants were presented with brief 500-Hz tones that were separated by inter-stimulus intervals (ISIs) of 500, 1000, or 3000 ms. Optic nerve hypoplasia manifests as a small optic nerve, which may or may not be accompanied by a peripapillary ring (the double ring sign). Distribution of Hp, Tf, Gc and Pi polymorphisms in a Nepalese population. Cell cycle progression and mRNA expression of cell cycle associated molecules were determined by flow cytometry and reverse transcription polymerase chain reaction (RT-PCR) respectively. Improving Decision making On Location of Care with the frail Elderly and their caregivers (the DOLCE study): study protocol for a cluster randomized controlled trial.