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Cycloxan (Cyclophosphamide)

Cycloxan belongs to a class of drugs called alkylating agents. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions. Cycloxan works by stopping or slowing the growth or spread of certain cancer cells.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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The purpose of this study was to investigate the changes in stimulated salivary flow rate, pH, buffer capacity, and the levels of mutans streptococci (MS) and lactobacilli in patients undergoing therapy with fixed orthodontic appliances. Process control methodology is easy to apply and potentially useful in monitoring hospital trauma mortality. Detailed examination of the light scatter and PI staining of Hoechst 33342-stained mammary cells enabled single live side population and non-side population cells to be defined with greater accuracy. We have thoroughly validated TBC1D2/Armus, a GAP of Rab7 GTPase, as a novel target of miR-17.

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The analysis of molecular variation showed that mostly of the detected genetic variation occurs at interpopulational level. Prognostic factors in adenoid cystic carcinoma of salivary glands In this study, the genetic contribution to age-related changes in sleep was assessed in three inbred mouse strains of various ages. This study presents a novel, non-transgenic, non-surgical method for induction of renal injury in hamsters, which is an important complement to existing diabetic models for pathophysiological studies in early acute and chronic kidney disease, especially hyperlipidemia. Gene expression changes were determined by microarray and analyzed with MeSH indicating brain regions.

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Haldane was called to investigate the ventilation and quality of the air in Cornish tin mines, since the miners suffered from fatigue or even fainted. PCR was performed with pharyngeal washings and revealed Legionella DNA, while no genetic materials of other pathogens such as respiratory viruses, Mycoplasma and Chlamydia were detected. JQ1 is a small molecule that blocks BET interaction with histones. Female urinary incontinence: a systematic review of qualitative studies The relative risk for stroke and passive smoking was derived by means of a meta-analysis from available cohort studies.

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Review: Mechanical and manual CPR do not differ for survival or neurologic outcome in out-of-hospital cardiac arrest. Alternatives to dual-energy X-ray absorptiometry (DXA) have been sought to increase access to low-cost osteoporosis risk assessment. To determine the role of CHK1 in the pathogenesis of lymphoid neoplasms and its relationship to other DNA damage response genes, we have analyzed the gene status, protein, and mRNA expression in a series of tumors and nonneoplastic lymphoid tissues. The quantification limit was 0.01 mg/L in plasma and 0.5 mg/L in urine.

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Fetal sex assignment in the late first and early second trimester can be useful in pregnancies at risk for severe sex-linked diseases, in fetal disorders involving the genitalia, and in the individual identification of multiple fetuses. These results help to reveal the evolutionary behavior of influenza viruses prior to their emergence in humans.IMPORTANCE The newly emerged H5N6 influenza A virus has caused more than 10 human deaths in China since 2013.

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Measurement of pepsinogen group I in endoscopic gastroduodenal biopsies. Variants of sagittal synostosis: strategies for surgical correction. The D-loop HVR II and HVR III regions of mtDNA in seven cases with OSCC tissues, matched with paracancerous tissues and normal mucosa tissues from the same case, were amplified by polymerase chain raction (PCR), then were detected by direct sequencing to find the mutantsites after the comparison of all sequencing results with the mtDNA Cambridge sequence in the GenBank database. Similarly, hormone supplementation also modified immune function and increased tissue vitamin E levels in uninfected mice.

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However, PCNA positive cells decreased over time in all groups, and there were no significant differences among the groups. Class-specific antibody response to Haemophilus influenzae type b capsular polysaccharide vaccine. Involvement of the pleural cavity by pseudomyxoma peritonei is rare and carries an unfavorable prognosis.

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Is physical activity, practiced as recommended for health benefit, a risk factor for osteoarthritis? Update on the heritability of inflammatory bowel disease: the importance of twin studies. In this review, we discuss theoretical approaches to understanding linear and nonlinear surface-enhanced vibrational spectroscopies. Groups of adult humans, previously unexposed to rabies and with no history of rabies vaccination, were inoculated with different schedules of phenolized inactivated vaccine and Flury strain chicken-embryo vaccine, with or without one inoculation of hyperimmune serum.

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Convergent validity of the bench to shoulder lift of the WorkHab FCE was not established as no relationship between the muscle recruitment using SEMG and SML, as determined by therapist observation was identified during this lift. Innate immunity represents a trait common to plants and animals, and besides the humoral factors different cell types e.g.

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Understanding the Mechanism of the Broad-Spectrum Antiviral Activity of Favipiravir (T-705): Key Role of the F1 Motif of the Viral Polymerase. The choice of one or the other option may be flexible, as when individuals respond to attractive dispersal options, or they may reflect fixed life-history trajectories. Meeting these needs can help these professionals to provide more appropriate care. The analysis technique used here is capacity independent and is novel in error analysis of ranking learning.

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Twelve week-old male Wistar rats were grouped as follows: control (C) group, hypertension (H) group, and losartan (L) group in which SHR was treated with losartan (10 mg/kg/day). An increased carrying angle of the elbow appears to be an independent risk factor of nontrauma-related ulnar neuropathy.

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Here, a grhl1 down-regulated zebrafish model exhibited inner ear developmental malformations, including missing otoliths, disordered and abnormal numbers of hair cells in the inner ear and lateral line, and sound insensitivity. The protein was purified in an active form and a spectrophotometric assay was developed in which the oxidation of NADPH was coupled to reduction of arsenate. Clinically, the average recovery of elbow flexion was comparable to conventional donors for 2-stage muscle transfer.

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Treatment is limited, with the bisphosphonates being the mainstay of therapy. By relying on random-effect models, this approach handles individually varying and outcome-specific measurement times. This combined strategy was rational, safe and more effective than either EEN or emodin used alone, and has a broad potential for future clinical application.

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Analysis of the parental strains led us to detect an important length polymorphism of chromosomes I and III in FL100trp. In this work a method is described for the clear separation and extraction of artemisinin from other plant components in the Artemisia annua L. Prolonged seizures increase proliferating neuroblasts in the adult rat subventricular zone-olfactory bulb pathway. This review will summarize the actions of GIP in human physiology and discuss its role in the pathogenesis of type 2 diabetes, as well as the therapeutic options derived from these findings.

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One of the patients they have followed for 25 years, and an other one for 20 years. The two subjects are intimately linked, but the focus of this review is limited to the anti-inflammatory effects of protease inhibitors. Effects on the central, somatic, and autonomic nervous systems, digestive system, urologic organs, and reproductive system This study analyzed the impact of heart transplantation on ventricular mechanics in growing children.

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Why should infectious disease physicians care for the hepatitis C-infected patient? Impact of ADMA (asymmetric dimethylarginine) on physiology with respect to diabetes mellitus and respiratory system BEAS-2B cells (human bronchial epithelial cells).

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GH1 gene could not be amplified in samples from the patient while her parents yielded one fragment of the expected size. A clinical study of BRI following trabeculectomy surgery to investigate risk factors by documenting historical data review from patients records, self-reported questionnaire specific to ocular surface symptoms and a repeat detailed clinical examination of the lid, ocular surface and tear film. Individuals with the Taq IB GA genotype may have a lower risk of UA.

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These studies suggest that the ability of EBP1 to activate ErbB2 signaling pathways results in increased lapatinib sensitivity. Mechanistic studies on chemical and biological one-electron oxidations of cyclic tertiary allylamines are being pursued with the aid of an electrochemical-electrospray ionization mass spectrometric based assay.

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HCV-related liver disease in hemodialysis population: clinical and biochemical characteristic Exacerbation of SLE has not been previously described following myelography with any contrast agent. Yeast two-hybrid screening of a bovine retinal cDNA library with the cytoplasmic domain of the retinal insulin receptor (IRbeta) identified a member of the Grb7 (growth factor receptor-bound protein 7) gene family, Grb14.

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Local perceptions and language may not correspond to CDC/WHO clinical standards. Detailed arthroscopic reports were then reviewed and compared with the MR findings documented before surgery, with arthroscopic findings being the standard of reference for comparison. Selection of medicines in Chilean public hospitals: an exploratory study. Use of the Incontinence Monitoring Record may provide nursing assistants with an easier and more comprehensive method of recording incontinence patterns. In this co-culture system, neurons and glial cells are cultured in two separate chambers that are connected through multiple central channels.

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Plasma levels of endothelin-1, nitric oxide, cholesterol, and HDL were measurement before and during treatment with both oral contraceptive treatments. Consideration of the key facilitators and barriers for programme implementation as highlighted in this study can inform future improvement efforts. A zebrafish model overexpressing the mutant hASRGL1 developed retinal abnormalities and loss of cone photoreceptors. There were no significant differences in SHBG levels between patients with PE, RCIU or controls (324.7 (26.6), 336.8 (33.9) and 377.5 (24.3) nmol/L, respectively).

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We used transgenic mice that express high levels of active TGF-beta1 and have elevated plasma levels of TGF-beta1 and wild-type mice of the same strain as controls. Vaccination supported a long term antibody response against PCV2 and a moderate but weaker antibody response against MHYO for early finishing pigs challenged with PCV2.

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Osseointegration was completed by 28 days after the procedure in both groups. Coexistence must therefore involve additional mechanisms beside the trade-off, but very little is known about the operation of such mechanisms in nature.

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These results demonstrate that the initial bleomycin-induced oxidative stress causes a direct apoptotic effect in lung epithelial cells involving a regulatory role of caspase-8 on caspase-9. Chromatographic identification of the antilipaemic X factor of the unsaponifiable fraction of crude vegetable oils. Age, sex, breed, clinical findings, feline immunodeficiency virus and feline leukaemia virus status (in cats), species of Cryptococcus causing disease and region of domicile were recorded. Immunocytochemical localisation of both lactoferrin and elastase was confined to neutrophils infiltrating cyst walls. It is necessary to assess bone mineral content of cortex especially in patients with lingering imbalance of bone metabolism.

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Clamps develop sequentially, with the younger, and eventually larger, clamps being anterior. Heart failure is a tremendous burden on society, and on the health care system in particular. The aggregate radiation exposure to all members of the department doubled subsequent to the introduction of an electrophysiology laboratory.

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The recent advances in our understanding of the histology, immunophenotype and pathogenesis of these KSHV-associated lymphoproliferative disorders are reviewed. Statistical analysis was performed using Instat GraphPad v2.05a statistical package software.

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Furthermore, IBZM binding is not consistent in melanoma patients. Interestingly, a caspase-independent mechanism was observed to be involved in the p53-induced apoptosis in U251-MG and D54 cells.

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Belief systems overlie powerful biological and psychological forces that are root causes of war. Residual dyslipidaemia in patients treated with statins needs to be addressed to reduce the prevalence of cardiovascular disease in primary and secondary care.

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In eukaryotic cells directional sensing is mediated by heterotrimeric guanine nucleotide-binding protein (G protein)-linked signaling pathways. Levels of experience and competence in palliative medicine vary considerably among physicians. Abciximab suppresses the rise in levels of circulating inflammatory markers after percutaneous coronary revascularization. The Pearson correlation test was used to determine the correlation between the amount of maxillary superior repositioning and the vertical and horizontal changes of the chin.

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Clinical nursing rounds: a model for elder care planning at the bedside. A real-time BCI system based on this approach is implemented and evaluated through an online experiment involving six subjects performing 2-D control tasks.

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In 33 cases, there was good correlation between the upright thin-section tomogram findings and the surgical results. Purification by affinity chromatography with anti-idiotypic monoclonal antibodies of immunoreactive monoclonal antibodies following labeling with 188Re. To verify the theory, a 16-element high-pass elliptical birdcage coil was built inside a circular RF shield. Lytic polysaccharide monooxygenases (LPMOs) are recently discovered copper-containing oxygenases.

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Although the majority of studies reveal the association between PTSD and sleep disturbances, there are few studies on the assessment of sleep disruption among veterans with PTSD. The choice of therapy in the management of refractory angina pectoris.

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Plasma somatomedin activity and urinary hydroxyproline excretion during administration of human growth hormone in children with short stature. Our data show that genetic polymorphisms in transporter proteins cause variation in hepatic exposure to metformin, and it demonstrates the application of novel imaging techniques to investigate pharmacogenetic properties in humans. Interlaminar and ductile characteristics of carbon fibers-reinforced plastics produced by nanoscaled electroless nickel plating on carbon fiber surfaces. This series examines the effect of public funding versus self-pay on patients undergoing LAGB over 1, 2 and 3 years. Additional studies are needed to clarify if this mechanism has a role in the adipocytic switch driven on osteoblasts by adipocytes inside bone marrow and if EVs could be a target component to regulate the competition between osteoblasts and adipocytes in the prevention or in the therapy of osteoporosis and other osteopenia.

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One of the most important problem in systems pharmacology is prediction of drug-target interactions. Benzidine test for detection of minimal vaginal bleeding in postmenopausal women. They possessed no ability to bind to or hydrolyze insoluble microcrystalline cellulose (Avicel) but were active toward soluble carboxymethylcellulose. epidermidis strains were isolated from cases of endophthalmitis, they developed after crystalline extraction and implantation of an intraocular lens. NORMAL values for urinary excretion of lead and corproporphyrin together with basophilic red blood cell count in Chinese.

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Interestingly, of the Epstein-Barr virus proteins on the array, the EBNA1 protein had the most similar kinase profile to LANA. The duplicate extracellular binding domains of MAEBL, responsible for erythrocyte binding, are the most conserved regions.

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Recent advances are helping elucidate the pathogenesis and improve the management of thyroid eye disease. Current guidelines in the pharmacological management of chronic heart failure.

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Probabilistic fiber tracking with 64 orientations detected the DRTT in all twelve hemispheres. We suggest that this hyper-induction of cytokines may be relevant to the pathogenesis of human H5N1 disease.

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Water from the primary water source and toenail samples were collected from each subject and tested for inorganic arsenic. We examined the immunohistochemical localization of beta-amyloid (Abeta) and beta-amyloid precursor protein (AFPP) in the neuronal and non-neuronal tissues of 14 aged (over 10 years old) and 4 young (0-4 years old) dogs.

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This paper uses an orthotropic shell model to investigate in detail the long axial wavelength circumferential vibration of microtubules (MTs). To our knowledge, this is the first report of BVDV RNA isolated from an Alpine chamois. Anatomical relationship between the medial head of the gastrocnemius and the occurrence of a dystrophic bony lacuna. We hypothesized that body mass index (BMI) affected the link between EAT and MS and CAD.

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However, intratumour heterogeneity, mucinous pancreatic duct hyperplasia harbouring K-ras mutations, and sampling error will hinder their diagnostic accuracy in routine clinical use. Data were generated at densities varying from 1 to 100 results per 1 km grid square in different parts of the map.

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Rorschach Comprehensive System data for a sample of 506 adult nonpatients from Argentina. This process led to essentially complete involution within 4 days, at which point estrous cycling recommenced. In contrast to the beta chain repertoire in which Vbeta8.2 with the shortest CDR3 is the predominant population throughout the course, multiple oligoclonal expansion was observed at all time points examined. Adjuvant chemotherapy was not conducted because of the delay of postoperative recovery despite III b staging. Though many bioaerosol studies have been conducted at animal production facilities, few have investigated the transport of bioaerosols during the land application of animal manures.

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Transmission-blocking drugs have only limited effects unless administered with a prophylactic under very high coverage. Revisions to the audible beaconing features resulted in improved performance on four measures of wayfinding as compared to the pre-installation condition: beginning crossings within the crosswalk, ending crossings within the crosswalk, independence in finding the starting location, and independence in aligning to cross. Atomic layer deposition of metal oxides on pristine and functionalized graphene.

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Although GSNO can strengthen the capacity of mature DCs to induce type 1 polarization of T lymphocytes, our data suggest that it elicits distinct anti-inflammatory functions, eventually reducing T lymphocyte proliferation and recruitment. The majority of patients operated on for mitral valve disease with chronic atrial fibrillation (AF) ofloxacin floxin 400 mg do not recover sinus rhythm with conventional postoperative treatment. Low testosterone in men is often accompanied by increased levels of estradiol. In the prefrontal cortex, the enzyme catechol O-methyltransferase (COMT) is critical in the metabolic degradation of dopamine, a neurotransmitter hypothesized to influence human cognitive function.

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Ankle braces in sports are used for prevention of ankle sprains. Effect of dietary sodium restriction on human urinary metabolomic profiles. Furthermore, C3G protein expression is significantly elevated in the non-infarcted myocardium of the peri-infarct zones. Optimizing metrocream 0 75 bei rosacea natural treatment conditions for calcium phosphate mediated transient transfection.

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We aimed to investigate clinical significance of Rab25 in prostate cancer (PCa). forcan tablet use in classroom To stress or not to stress: Physiological responses to tetrodotoxin in resistant gartersnakes vary by sex. A 48-year-old man with systemic lupus erythematosus (SLE) was admitted with fever, headache and mental change.

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We found that insurance and advertisement respectively are the most effective on increasing the frequency of prescribing, whilst negative correlation was observed between price and the frequency of prescribing a drug. Serum trupan mdf argentina vs brazil FGF21 concentrations are markedly elevated in patients with T2RN. Its efficacy in case of sudden deafness, non-exclusive of other causes than ischemia, is being assessed in a multicentric project.

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Crude xylem extracts from katsura tree (Cercidiphyllum japonicum), of which XPCs exhibited deep supercooling to -40 degrees C, were prepared by methanol lamitor overdose extraction. Expression of early placenta insulin-like growth factor (EPIL) in breast cancer cells provides an autocrine loop with enhancement of predominantly HER-2-related invasivity Furthermore, in a more general context, the direct and indirect effect on the individual patients is discussed and recommendations are given on how to use scoring systems. However, none of these indexes showed any significant correlations during the first 24 hours following surgery.

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This field offers dentists opportunities to participate in a tremendously rewarding area of medicine, but requires due diligence to participate responsibly in that field. Social media is still considered by many to be a tool of frivolity, best limited to personal rather than business use, or perhaps at best only omeprazole over the counter substitute for nasonex of real commercial utility in business-to-consumer applications. Synthesis and evaluation of amino acid esters of 6-deoxypenciclovir as potential prodrugs of penciclovir.

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Hardness and elastic modulus of these materials were measured by nanoindentation using a nanoindenter. High-tech medicine in the Caribbean: 25 years of Cuban health care. There was, however, a significantly higher incidence of ischemic pain in the symptomatic patients. Ninety-one of 479 patients with an inguinal hernia during the study period did ziagen package insert pdf into publisher not meet the exclusion criteria, and 46 were allocated to Marcy repair and 45 were allocated to Prolene Hernia System repair. The diaphragm was affected more severely than proximal or distal muscles of the extremities.

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Review of three additional cases of abdominal tuberculosis showing these findings supports the criteria defined in the earlier study. Herein we present a detailed study of the photokinetics and photoproducts of nucleosides caged with aspirin clopidogrel and clexane dose these new protecting groups. The solubility of proteins were reduced as influenced from the aqueous and gas ozonation medium. Data from the MTT assay were tested statistically using SigmaStat 3.5.

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All other amino acids and peptides examined had little or no effect on the autooxidation rate of ascorbic acid. Patellofemoral maltracking is a recognized deptran l tab organizer cause of peripatellar pain. The digital geometric data were exported to print the solid model with rapid prototyping system. 2) A reversion to virulence study, where horses were vaccinated with a 20x immunogenicity overdose of WN-FV chimera vaccine.

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The calculation of these thermodynamic quantitites was limited in the past by their slow convergence relative to the free energy. Hip strength may directly relate to abnormal ortanol 20 plus 20 mg vyvanse running mechanics and contribute to the high incidence of overuse injuries in distance runners. In nature, mussel adhesive proteins (MAPs) show remarkable adhesive properties, biocompatibility, and biodegradability.