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Endoxana (Cyclophosphamide)
+ BONUS
 
Cyclophosphamide

Endoxana is type of drug known as a disease-modifying anti-rheumatic drug (DMARD). It’s used to treat an overactive immune system by targeting cells that cause harm to healthy tissues. It’s an effective treatment for many people who have developed serious complications as a result of their condition.

Other names for this medication:
Cyclophosphamide, Cytoxan, Ciclofosfamida, Cryofaxol, Cycloblastin, Cycloxan, Cycram, Endoxan, Endoxana, Genoxal, Neosar, Procytox, Sendoxan,

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The Pan-University Network for Global Health: framework for collaboration and review of global health needs. In an earlier attempt to develop peptide mimotopes capable of preventing the anti-MIR-mediated pathogenicity, the peptide Pep.1 was initially identified from phage display, and subsequently, Cyclic extended Pep.1 (Cyc.ext.Pep.1), which incorporates eight additional residues into the Pep.1 sequence and has an affinity for the anti-MIR antibody mAb198 3 orders of magnitude greater than that of Pep.1, was developed.

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Development of key anchors for the scale, specific to the disorder being assessed, holds promise for enhancing the validity and reliability of the measure for disorders such as Rett syndrome. Bypass grafting presents an ideal opportunity for gene therapy, as surgically harvested vein grafts can be treated with gene delivery vectors ex vivo, thereby maximizing gene delivery while minimizing the potential for systemic toxicity and targeting the pathogenesis of vein graft disease at its onset. This method appears to be a good alternative for patients with severe renal impairment or allergic problems. Unclear-onset strokes are generally excluded from time-based thrombolytic therapy.

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Although increased SUA is not necessarily a causal risk factor, our results suggest the clinical importance of monitoring and intervention based on the presence of an increased SUA concentration, especially because SUA is routinely measured. In the present study, we report the characterization of Hm-MyD88 and Hm-SARM. Some of them belong to central neurons responsible for efferent innervation of the pond snail eye.

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Municipal solid waste originating from abandoned landfills closed in the seventies represented stable material. We have sequenced a part of the cloned lux region and identified the luxA, luxB and luxG genes encoding the alpha and beta subunits of luciferase and a gamma protein with an Mr of 26,180, respectively. The importance and the reason of the efficacy of cortisone therapy of neorickettsial diseases are demonstrated by the behavior of the experimentally infected Malurus We demonstrated in RA FLS that ELMO1 is: (i) expressed, (ii) promotes cell migration and invasion, and (iii) regulates Rac1 activity.

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Both HTS and nafamostat reduced T/HS-induced pulmonary permeability and neutrophil sequestration, as well as neutrophil activation as compared with resuscitation with RL. Gape size, its morphological basis, and the validity of gape indices in western diamond-backed rattlesnakes (Crotalus atrox). No patient with follicular adenoma had any further difficulty after removal of the lesion.

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It also found that FBXW7 siRNA reverses the suppressive effect of FAM83D knockdown on Notch1 protein expression. Our findings confirm the prognostic role of CAF-1 p60 and indicate TMA as a really advantageous method for CAF-1 p60 immunohistochemical screening, allowing savings on both tissue quantity and operator-time.

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Fluorescence, electron paramagnetic resonance (EPR) spectroscopy and molybdenum quantification based on inductively coupled plasma emission spectroscopy (ICPES) clearly indicate that, in the absence of NarJ, no molybdenum cofactor is present in the NarGH complex. In itinerary profiling, structural clusters included in a trajectory are represented by a bit sequence, and a number of trajectories, as well as the structural clusters, can be compared and classified. For short electrode separations less, similar 1 mum the current mainly flows through the two outer shells, described by a resistive transmission line with an intershell conductance per length of approximately (10 kOmega)(-1)/microm. Recently, we characterized a thiyl radical-dependent mechanism for the photolytic conversion of a disulfide bond in a model peptide into dithiohemiacetal and subsequently into thioether ( Mozziconacci et al.

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Electroconvulsive shock, retrograde amnesia, and competing responses. ELISA and plaque reduction neutralization tests were performed to detect anti-orthopoxvirus antibodies. Vibrational modes of the chromophore and the surrounding protein are excited with a femtosecond IR pump pulse, and the subsequent vibrational dynamics in the chromophore are selectively probed with a visible probe pulse through changes in the absorption spectrum of the chromophore. The resulting fluorescent polymer particles were analyzed by absorption spectroscopy and by steady-state and time-resolved fluorescence spectroscopy including measurements of the fluorescence anisotropy.

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Bacteriostatic activity curves of combinations of colistine with tetracycline and kanamycin Additionally, TMT in vivo did not increase oxidized glutathione (GSSG) levels, nor did it alter hepatic ATP content.

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It also illustrates the complexity involved in the formation of some structurally abnormal chromosomes, which can only be resolved by detailed molecular investigations. Phagocytic capacity of the reticuloendothelial system and purification of the lungs from dust In this paper it is shown that, when contact noise is present, the experimental values of the normalized Hooge parameter show a fictitious linear dependence on the volume of the analyzed samples. The aim of our study was to screen virus genomes in heart tissues from heart-transplanted patients to prove their possible role in the pathogenesis of dilated cardiomyopathy.

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The advantages in terms of both surgery of tumour excision and tissue preservation are discussed. Given the emerging evidence that MP is important for visual performance and comfort, and given the putative protection that this pigment confers against AMD (especially important in the context of increased risk of AMD in this social group), public health measures aimed at improving diet for this at-risk population need to be considered.

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The threshold test used various concentrations of butanol presented in an ascending sequence. Preoperative audiological evaluation, intra-postoperative electrically evoked auditory brainstem response (EABR) and neural response telemetry (NRT) record for the two cases were conducted in Beijing Tongren Hospital. Increased morbidity associated with weekend paediatric road traffic injuries: 10-year analysis of trauma registry data. Each type of neuron formed small groups or clusters in the nucleus so that several successive recording sites typically encountered one type before a sequence of the other type was observed.(ABSTRACT TRUNCATED AT 400 WORDS) This finding supports the classic motivational perspective of Leon Festinger on the selective exposure effect.

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This CT dataset and additional data provided by other researchers was used to reconstruct a second dataset containing 3D models of the left lower jaw for 153 individuals representing 94 extant shark species. A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature. Although the loss of wild-type BRCA1 function is an important mechanism by which mutations confer increased cancer risk, multiple studies suggest mutant BRCA1 proteins may confer functions independent of the loss of wild-type BRCA1 through dominant negative inhibition of remaining wild-type BRCA1, or through novel interactions and pathways. Tricotillometer is a useful device to measure the EF in various physiological and pathological conditions and may have diagnostic, prognostic, and therapeutic value in various hair diseases.

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Conditions of the obtaining polymer compositions, containing protease C, lysozyme and polysacharide sodium alginate and their properties were developed and investigated. A qualitative study was conducted among a range of health workers at different levels of the health system in the Brong Ahafo Region of Ghana.

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Bacillus thuringiensis accumulates, primarily during sporulation, large quantities of insecticidal protoxins which are deposited as crystalline, intracellular inclusions. The risk of treatment for benign prostatic hyperplasia/lower urinary tract symptoms was determined by calculating the hazard ratio using the Cox proportional hazards model. Metal-dimer atomic reconstruction leading to deep donor states of the anion vacancy in II-VI and chalcopyrite semiconductors. Evidence base of clinical diagnosis: Rational, cost effective use of investigations in clinical practice.

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However, unlike other platyrrhines in which three M/L photopigments are typical, Callicebus has a total of five M/L cone photopigments. Total excision was achieved and the postoperative course was uneventful. Contributions on the relation between blood groups and chronic benzene poisoning

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For reasons of cost efficiency and practicability, the urea dose and measurement duration should be reduced while still maintaining excellent diagnostic accuracy. Early outpatient initiation of NIV in ALS is as effective as inpatient initiation. We provide further verifiable consequences of this phenomenon, and several additional comparisons between theory and experiment.

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Large-scale screening for developmental genes in embryonic stem cells and embryoid bodies using retroviral entrapment vectors. An unusual cause of hematemesis in the newborn infant: stomach teratoma. saman with dual rhizobial and mycorrhizal infection is a potential tree for plantation in arid soils of Pakistan. These distributions of 3H were changed with growth phase and/or incubation time. DNA damage in irradiated cells that has not been correctly restored by metabolic repair processes is conventionally regarded as the reason for the adverse consequences of radiation exposures.

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Phenylephrine testing can help in fine-tuning the amount of resection, but given the mechanism of action of MMCR, adequate levator muscle function remains a critical factor in the success of the surgery. Microtubules decorated with kinesin-related ncd motors are used as model aggregates to demonstrate the utility of this package of routines.

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Early light microscopic studies of the biflagellate green alga Chlamydomonas revealed a fibrous system, the neuromotor apparatus, which appeared to link physically the flagellar apparatus to the cell nucleus. The present study aimed to characterize the interactions between M.

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All studies were carried out in pediatric oncology and deal with exercise therapy. The dose-response curves shifted to the left with increasing inspired concentrations of enflurane and halothane, thus indicating an increase in neuromuscular blocking potency. The average patellar flexion increase peaked at 4.4 degrees at 45 degrees flexion. Our findings indicate that (131)I, after NIS gene transfer, can effectively prolong cardiac allograft survival.

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The background was clean, and this finding pointed to the noncervical origin of the malignant cells. Recent data indicate that renal L-Arg transport plays an important role in regulating both renal perfusion and function and the long-term set point of arterial pressure in health.

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Using stable isotopes of calcium and leucine, we determined calcium absorption, urinary calcium loss, calcium retention, deposition into bone, leucine rate of appearance from protein, leucine incorporation into protein, and leucine oxidation in seven girls (10-17 y of age) and four adult females (16-34 y of age) with Turner syndrome, before and after 3 mo of GH treatment. A search of PubMed, CINAHL and Medline databases produced 1930 combined hits. Conducting forensic examinations on the road: are you practicing your profession without a license? Seventy three patients with hyperlipoproteinemia, aged from 40 to 69 years, were included in the study. Carcinoma of the oral cavity--analysis of local metastases and results of therapy

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To describe the demographic characteristics of patients with spontaneous subarachnoid haemorrhage (SAH) in our population and to compare the endovascular and surgical treatment of intracranial aneurysms. High concentrations of amiodarone and its desethyl metabolite were found in tissue samples, with fat forming a potentially large tissue reservoir of the drug. Formulation components appeared to have the most significant impact on redispersibility of spray dried particles.

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To our knowledge, post-keratoplasty endophthalmitis caused by P. All patients were treated with 5 mg/kg of carbamazepine once per day until the diarrhea had stopped, i.e.

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This study was undertaken to determine whether GIK infusion improves hemodynamic performance by reducing the use of inotropic agents, as well as the morbidity of diabetic patients submitted to CABG. Prevalence of white spot syndrome virus (WSSV) was determined using polymerase chain reaction (PCR) methodology on DNA extracted from the gills of wild black tiger shrimp Penaeus monodon collected from 7 sampling sites in the Philippines. The ability of the United States to most efficiently make breakthroughs on the biology, diagnosis and treatment of human diseases requires that physicians and scientists in each state have equal access to federal research grants and grant dollars. Mechanism-based inhibition of rat liver microsomal diazepam C3-hydroxylase by mifepristone associated with loss of spectrally detectable cytochrome P450.

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Evidence of residual disease in ossicles of patients undergoing cholesteatoma removal. Quantitative vessel flow imaging was useful in subsequent medical management and decision making to perform therapeutic angioplasty/stenting to preserve flow. The objective was to conduct a systematic review and meta-analysis of studies that compared energy-restricted, isocaloric, high-protein, low-fat (HP) diets with standard-protein, low-fat (SP) diets on weight loss, body composition, resting energy expenditure (REE), satiety and appetite, and cardiometabolic risk factors. 4) Exchanging the central domains perturbed the conformational stability of the protein. We underline that the renewal theory is applicable to analysis of suprathreshold responses even of resonant neurons.

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The inhibition of GAD(67) mRNA expression in hippocampus was selectively induced by antisense oligodeoxynucleotide of GAD(67). One year later, despite many changes having taken place, midwifery morale was still low but participants were more politically analytical of, and actively involved in changing their situation. However, aprotinin marketing was temporarily suspended in 2007/2008 based on results from a randomized study indicating a risk for increased mortality associated with the use of aprotinin.

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There are disadvantages in investigating successfully completed suicides which make suicidal ideation and previous attempts important proxy measures of suicidal risk. 65:279-308, 2003) as well as the fact that enzyme systems, in which the interconversions between the different enzyme species involved are of first or pseudofirst order, act as linear compartmental systems, we hereby carry out a complete analysis of the mean lifetime that the enzyme molecules spend as part of the enzyme species, forms, or groups involved in an enzyme reaction mechanism.

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Fibrosis is a prominent pathological feature of muscle biopsies from patients with DMD. The determination of molecular weights for certain proteins has been performed. Perceived welfare caseworker support and psychological distress among low-income urban women with children.

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There was strong interference between various virulent and avirulent strains of Semliki Forest virus (SFV) and their respective defective interfering (DI) viruses but in other combinations interference was variable: it could be equally strong, weak or could not be demonstrated. Persistent airway colonization with Alcaligenes xylosoxidans in two brothers with cystic fibrosis. A large rehabilitation hospital in the Southeast, with the collaboration of two Midwestern hospitals. More than half of the women reported a history of suicidal ideation or attempts.

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In these calculations, the free enzyme was found to have a negative (-1 e) charge per monomer at pH 7. Despite the fact that extracellular signal-regulated kinase/mitogen-activated protein kinases (ERK/MAPK) have been shown to be necessary for amygdala-dependent long-term potentiation and some forms of long-term and STM, inhibition of the ERK/MAPK signaling cascade by U0126 (2.0 or 4.0 microg) in the BLA was not critical for updating the STM of either spatial information or reward expectation. The relationship between argyrophilic proteins and some immunophenotypic markers in acute leukemia cells. (Otoneoplasty with recovery of the cartilage of the amputed auricle)

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Syntheses and structures of bora-amidinate lanthanide(III) complexes. Throughout most of the ovulatory cycle, estrogen negative feedback restrains the GnRH neuronal system.

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Fast polygon-based method for calculating computer-generated holograms in three-dimensional display. The patient was treated with transcutaneous electrical stimulation for 6 months and a physical therapy regimen focusing on periscapular strengthening. It is consistently detectable at depths up to 10 cm from the transducer.

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In the present study, we generated transgenic medaka that expressed green fluorescent protein under the control of the gnrh1 and gnrh3 promoters for analyzing forebrain GnRH neuronal development. We studied the cardiopulmonary responses to intravenous infusion of carbon dioxide, nitrous oxide, argon, helium, and nitrogen in anesthetized swine.

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Both classical tri-cyclic antidepressants and selective serotonin uptake inhibitors can frequently cause adverse effects in multiple dimensions of sexual function. Second, it will explore qualities in nurse-patient relationships that can be not only helpful to those who are cared for but also can be a mode of sustenance to the nurse. To answer this question, we have analyzed grading systems in this study. Black Africans display a more pronounced cold pressor test-induced rise in heart rate and blood pressure, which may be explained by greater pain-related increments in blood pressure. Three health states are defined for patients with curative resection of colorectal cancer: alive without relapse, alive with relapse, and dead.

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The determination of the post-mortem interval (PMI) of skeletal remains is a challenging aspect in the forensic field. Classification of chemical compounds into compound classes by using structure derived descriptors is a well-established method to aid the evaluation and abstraction of compound properties in chemical compound databases. Gengnianchun, terazosin brand name a Traditional Chinese Medicine, Enhances Oxidative Stress Resistance and Lifespan in Caenorhabditis elegans by Modulating daf-16/FOXO. Maternal obesity pre-programmes offspring to develop obesity and associated cardiovascular disease. After anemia correction, hemoglobin was maintained by roxadustat at various dose frequencies without intravenous iron supplementation.

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Diagnosis depends primarily on clinical features, biochemical parameters and the presence of the Kayser-Fleischer ring. The following case report describes an episode of subacute, life-threatening bleeding, after a Le Fort I osteotomy for the treatment of midface hypoplasia. To analyze the influence of several genotypes on the pattern of mutations developed and on values of viral load and alanine aminotransferase (ALT) after their development. Expression of B-cell CLL/lymphoma 2 (Bcl-2) and X-linked inhibitor of apoptosis (XIAP) and their mRNA were assessed by reverse transcriptase valavir medicine wheel (RT)-PCR and western blot analysis after treatment with minocycline alone and consecutive incubation with 200 microM H(2)O(2) and TGF-beta2. Modern diagnostical methods and treatment of geriatric patients depend on the course and nature of cerebrovascular diseases.

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CGS 16949A and tamoxifen combination: Increased food intake and body weight noted after CGS 16949A treatment were also observed following combination treatment, though to a lesser degree. Our case focuses on the idea that Arnold- Chiari malformation should be included in the list of abnormalities reported in NF-1. Studies of the medial temporal lobe and basal ganglia memory tadalafil effective dose of cialis systems have recently been extended towards understanding the neural systems contributing to category learning. Cellular senescence, which can be defined as a stress response preventing the propagation of cells that have accumulated potentially oncogenic alterations, is invariably associated with a permanent cell cycle arrest.

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The pathogenesis still remains unclear, and therapy often proves unsatisfactory. Comparisons of the genomes of PCC 7806 and other cyanobacterial strains indicate that a similar strategy may have also been used by the marine strain Crocosphaera watsonii WH8501 to adapt to other ecological niches, such as oligotrophic open oceans. In these postgenomic times where aspects of functional genetics and character evolution form a focal point of human-mouse comparative research, primate phylogenetic research gained a widespread interest in evolutionary biology. With the purpose of determining the course of the non-operated post-catheterization brachial artery thrombosis, 45 patients in this condition were followed during a one month period of survey. Furthermore, weak electrostatic complementarity between Asp77 on the amitriptyline 25 mg price alpha1 helix of Kb and 2C is enhanced in the allogeneic complex by closer proximity of QL9 peptide residue AspP8 to the 2C HV4 loop.

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Metabolic modeling of denitrification in Agrobacterium tumefaciens: a tool to study inhibiting and activating compounds for the sutrim antibiotic eye denitrification pathway. The solar water heating system is inexpensive, easy to transport and set up and could provide safer drinking water for 50 people a day. Thus, some degradation accompanied interaction of AII and platelets. However, evidence for other aspects of occupational therapy is still scarce, and better-quality trials are needed. HIV and Plasmodium falciparum malaria co-infection annually complicates about one million pregnancies in sub-Saharan Africa.

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As an inter-community effort, we have made a substantial update to GO in the exRNA veltride review of systems context. States used analytic strategies in an iterative process to investigate contributors to infant mortality. Synthesis, characterization and antiproliferative activity of metal complexes with the Schiff base derived from the condensation 1:2 of 2,6-diformyl-4-methylphenol and 5,6-diamino-1,3-dimethyluracil.

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The action of any lossless multilayer is described by a transfer matrix that can be factorized in terms of three basic matrices. Effects of esmolol rexan battlecon online on haemodynamic response to CO2 pneumoperitoneum for laparoscopic surgery.

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Reconstruction of the eyelids and associated orbital structures after resection requires a complete understanding of the anatomy. Zero-order correlations showed that violations and speed in the xylar meaning of name simulator were predictive of self-reported on-road violations. Eleven consecutive patients (9 women, 2 men, mean age 47.2 years) were retrospectively reviewed from a prospectively acquired neuroradiological database. In this case, black and white region represented the kidney and the background respectively. Microlaryngeal surgical simulation is a tool that can be used to train residents to prepare them for phonomicrosurgical procedures at all levels of training.

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In particular, physical forces account for interpersonal collisions, whereas social components include the individual desire to remain sufficiently far from other walkers (the so-called territorial effect). The disease is a late onset autosomic recessive metronidazole oral liquid for dogs condition, especially frequent in Caucasians. Ligand dynamics and early signaling events in the heme domain of the sensor protein Dos from Escherichia coli. For better compliance, the first re-examination should be scheduled at 3 months after the baseline visit.

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Further studies regarding multiple health behavior targeting interventions for adolescents are required. Microbiological diagnosis of deep respiratory tract infections from the clinical viewpoint coli it was shown that a GalNCO-CF3 next to the minimum binding epitope Galalpha1-4Gal did not substantially influence the binding, as did not warfarin dose management affects inr control a trifluoro acetyl group on the ceramide. Pharmacology and potency estimation of chlorothiazide and thiazide derivatives.