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Logistic regression revealed that lipasin was independently and significantly associated with retinopathy even after adjustments for confounders. Real-time motion compensated patient positioning and non-rigid deformation estimation using 4-D shape priors. Patient factors and oncologic factors determine the indication of prosthetic reconstructions.

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In a lens cell, two immiscible dielectric liquids but with different dielectric constants are sandwiched between electrodes. In the yeast Saccharomyces cerevisiae, the cytochrome c oxidase associates with the bc1-complex into supercomplexes, allowing efficient energy transduction. Furthermore, adequate parameters for the drying progress are extracted from the THz pulse-echo signal and effectively applied to monitor the wet-to-dry transformation. Patients were recruited within 24 hours of onset and used MRI based selection or outcome criteria.

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All tests were culturally acceptable with good psychometric properties. Recent studies indicate that the NF-L mutations reported in human Charcot-Marie-Tooth (CMT) disease lead to the formation of NF-L aggregates and result in axon degeneration of motor and sensory neurons, which are thought to be the cause of CMT disease type 2E. We compared the expression levels of several selected oncogenes in nontransfected (80PC), vector-transfected (80PCV), FSHR-transfected IOSE (80PCF) cells, and established ovarian cancer cell lines (OVCAR-3 and SKOV-3). The cheek advancement avoids creating a secondary defect and because it involves less dissection and additional skin incisions, is an easier procedure to perform with fewer facial scars.

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In general, such biomaterials are characterized by antifouling coatings, exhibiting low adhesion or even repellent properties towards microorganisms, or antimicrobial coatings, able to kill microbes approaching the surface. In contrast, methylmercury-chloride complexes, which are dominant in marine systems, were unreactive. Prevention and regeneration of barrier disturbances in occupational dermatology

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Obesity is a common medical disorder in dogs, and can predispose to a number of diseases. Affective disorders, mainly depressive and bipolar afflictions are life-long recurrent diseases and require constant treatment and prophylaxis.

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Autophagy inhibition is being evaluated as a novel therapeutic strategy in multiple tumor types, but little is known about its implications for metastatic dissemination. Therefore, this may be the first sign of vulnerability to sounds. Gastroesophageal pressure gradients in gastroesophageal reflux disease: relations with hiatal hernia, body mass index, and esophageal acid exposure.

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Immuno-SERS microscopy is a novel imaging technique in nano-biophotonics, which employs antibodies labeled with SERS-active nanoparticles in conjunction with Raman microscopy. Whispering-gallery-mode laser at 1.56 mum excited by a fiber taper. IgE immunodetection of synthetic peptides led to the identification of Pru p 3 sequence regions 11 to 25, 31 to 45, and 71 to 80 as major IgE epitopes. DNA secondary structures and the evolution of hypervariable tandem arrays. Nuclear factor kappaB signaling in opioid functions and receptor gene expression.

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The binding of viral fragments to the CD4 peptide-Sepharose beads was ascertained either by aid of a ninhydrin reagent or by fluorescence microscopy. Since mucins are considered, to a large extent, responsible for the viscoelastic properties of the secretions, the enhanced levels of the highly sulfated mucin component in the secretions of the patients with increased disease severity, may contribute to altered rheological properties and hence decreased mucociliary transport of the secretions. A strong anion-exchange functionality on a pH-stable polymeric particle was used to investigate the selectivity and resolution of the technique.

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That is, the language experience effect (i.e., a stronger N1 response to familiar writings than to unfamiliar writings) was significant only for alphabetic letters, but not for alphabetic and logographic words. Nevertheless, this realistic modeling makes way for future investigations, in particular to examine the characteristics of pre-processing strategies. The association between selected risk factors for pancreatic cancer and the expression of p53 and K-ras codon 12 mutations. Recent models of motor adaptation derive from assumptions about the way the motor apparatus changes. Nascent very low density lipoprotein (VLDL) exits the endoplasmic reticulum (ER) in a specialized ER-derived vesicle, the VLDL transport vesicle (VTV).

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In addition, the possible need for an extra-intracranial bypass prior to tumor removal should be evaluated. We have therefore adapted and developed methods of analyzing oligonucleotides by matrix-assisted laser desorption ionization mass spectrometry to the quality control situation, resulting in the ability to analyze 20 oligonucleotides up to at least 40 bases long in less than an hour. Even though the ischemia-induced gene expression has a dichotomy to beneficial and harmful genes, several genes such as those encoding transcription factors may participate in both cellular responses.

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The authors present the results obtained during an audiometric screening of 153 children aged 5-18 years, affected by beta-thalassemia and treated with regular blood transfusions and iron overload chelation by means of desferrioxamine. Four miRNAs, including microRNA (miR)-9-5p, miR-9-3p, miR-181d, and miR-130b, exhibited an inverse correlation with IGF-1 levels. N-WASP is highly expressed in hepatocellular carcinoma and associated with poor prognosis. Assessing the calorific significance of episodes of human cannibalism in the Palaeolithic. Eleven hundred and sixty-six participated in 1989 and 1011 of them participated in 1991.

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The physiology of bone loss in aging women and men is largely explained by the effects of gonadal sex steroid deficiency on the skeleton. Hypoglossal nerve palsy as a complication of transoral intubation for general anesthesia. Vitamin D in European children-statement from the European Academy of Paediatrics (EAP). Effect of a streptococcal preparation (OK432) on natural killer activity of tumour-associated lymphoid cells in human ovarian carcinoma and on lysis of fresh ovarian tumour cells.

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Various kinds of contraction-associated molecules are up-regulated at the initiation of labor. Thus we hypothesized that renal cell injury resulting from apoptosis is involved in renal failure with severe acute pancreatitis. The total blood loss and hidden blood loss are higher in the HA patients than in OA patients during total knee arthroplasty, although the external blood loss is basically the same. The eleven members of the membrane-associated RING-CH (MARCH) ubiquitin ligase family are relatively unexplored. However, to prove causality between cysteinyl leukotrienes overproduction and occlusive lower limb ischemia, a clinical trial with leukotrienes modifying drugs would be required.

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Sphere-forming-cuboidal cells are poorly differentiated and produced anaplastic tumors. Adoptive transfer of spleen cells from 20-wk-infected donors into acutely (6-wk) infected recipients increased granuloma mast cell density. The aim of this study was to compare the bilateral reading performances within the first 12 months after the implantation of two intraocular lens (IOL) models. have been improved in respect to environmental and economical concern. Dynamic imaging of autophagy-lysosomal pathway and autophagy function following pulmonary hypoxia/reoxygenation in vitro.

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No workers in the surveyed facility were found to suffer internal exposure beyond the recording levels, and their intakes were estimated to be below the detection limits in the 2-y investigation period. Preventing the development of disability in activities of daily living is an important goal in older adults, yet relatively little is known about the disabling process. Early fetal hypoxia leads to growth restriction and myocardial thinning. The agonist IL-1beta also increased significantly for BPD patients early, both compared to non-BPD patients, and also within the BPD group.

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Experiences with the muscle-relaxing agent Quilil in the treatment of diseases of the locomotor apparatus Transient isolated thyrotropin deficiency associated with cavernous sinus syndrome.

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Noise exposure--action level criteria as a predictor of permissible exposure level criteria. Strychnine also changed the shape of hip flexor ENG bursts, resulting in more abrupt burst onsets, indicating an earlier recruitment of motor neurons with large ENG spikes. There was no improvement in outcome with ESI whether patients were treated surgically or nonsurgically. Parenteral administration of GM1 ganglioside to presenile Alzheimer patients. Expression analyses in myeloid cell lines revealed induction of RGS2 during granulocytic but not during monocytic differentiation.

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Overweight/obesity and underweight are both risk factors for fractures at different sites. A nonocclusive roller pump combined with stiff and elastic tubing segments (for aortic pressure regulation and venous capacity) as well as constant and variable resistance (and optionally a patent duct) are essential features of the NMC system. This simple technique, which has worked successfully on both enzymatically and autoradiographically labelled material, provides a means by which retinal wholemounts can be cut nearly parallel to the plane of the retinal layers.

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This results in upregulation of cyclins B1, D2, and D3, and CDK1. Temperature, respiration, pulse, arterial pressure and blood composition in inhabitants of the city of Mary during spring and summer season Using microscopic sections of the kidney from 153 autopsies (99 SIDS infants and 54 control infants) in the National Institute of Child Health and Human Development (NICHD) Cooperative Epidemiologic Study of Risk Factors for SIDS, we counted relative numbers of sclerotic glomeruli in four fields of renal cortical tissue in two sections from each infant.

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Involvement of the tongue with solitary angiokeratoma, without a systemic or metabolic disease, is very rare. A second 1.0-cm skin incision was made along the upper margin of the mammary areola on the tumor side for insertion of a 12-mm trocar. Epithelial cells from PCOS patients were reprogrammed to pluripotency by retroviral transduction using defined factors.

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Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile cells. Evaluation of corneal topography with Orbscan II in first-degree relatives of patients with keratoconus. From these data we conclude that E1-deleted adenoviral vectors are not inert gene-transfer vectors and contribute to the modulation of the cellular differentiation pathways.

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Possible genetic association between interleukin-1alpha gene polymorphism and the severity of chronic polyarthritis. Biofilm consumption and variable diet composition of western sandpipers (Calidris mauri) during migratory stopover. Molecular stability and function of hemoglobins Hasharon (alpha(2)47 (CD5)Asp----His beta 2) and Hasharon (alpha(2)47 (CD5)Asp----His delta 2). Development and validation of an automatic treatment referral system.

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Information on socio-demographic characteristics, clinical and biochemical data, diet, physical activity, smoking, depression status, cognitive status and anthropometrics measurements, were obtained for all participants. These findings are consistent with results from previous studies, demonstrating that EEG alpha power is positively associated with a family history of alcohol use disorders. Methodology and research on the prognostic use of psychological tests.

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Isolation and biochemical characterization of extracellular polymeric secretions (EPS) from modern soft marine stromatolites (Bahamas) and its inhibitory effect on CaCO3 precipitation. The control values also were elevated when compared with normal values in Nigerian adults. The novel compounds (12 peptide and 7 nonpeptide ligands) were pharmacologically investigated in a calcium mobilization assay and in the mouse vas deferens bioassay.

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Our day surgery activity has had some negative aspects both for the availability of operating rooms and for the possibility of improvement of specific skills in our health staff. MMPs comprise a family of proteolytic enzymes implicated in the degradation of extracellular matrix which has been proposed to be one of the essential steps in tumor invasion and metastases. Bacterial adherence and invasion assays of eukaryotic cells and in vivo virulence studies of cellulose-deficient mutants indicated that, at least under our experimental conditions, the production of cellulose is not involved in the virulence of S.

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Properties and heterologous expression of the glucose transporter GHT1 from Schizosaccharomyces pombe. This primary sensory PNP may affect the majority of patients after administration of certain cumulative dosages of PAC, while the exact mechanisms of PAC-induced PNP are not known.

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Contrary to the published report that the reductive tricarboxylic acid cycle operates in A. MTS were produced from a PC-10 squamous lung carcinoma cell line. Biosynthesis and intracellular trafficking of lysosomal hydrolases (hexosaminidases, acid sphingomyelinase and ceramidase) and lipid binding and transfer proteins (GM2 activator, saposins) were analyzed to identify the molecular and metabolic basis of several sphingolipidoses. Novel through-the-scope technique for biliary plastic stent removal/exchange. A 70-year-old male who had undergone gastrectomy due to gastric cancer 6 years previously visited our department complaining of perineal and bilateral scrotal mass.

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Unmet needs of families of adults with mental illness and preferences regarding family services. Toric IOLs (T-IOLs) are, therefore, an excellent alternative for this condition. The primary outcome measures were the number of patients whose obstruction was successfully treated without surgery and the length of hospital stay. Noninvasive near infrared spectroscopy measurements were performed to monitor cyanide (CN) poisoning and recovery in the brain region and in foreleg muscle simultaneously, and the effects of a novel CN antidote, sulfanegen sodium, on tissue hemoglobin oxygenation changes were compared using a sub-lethal rabbit model. As drug-induced ILD is often reported in Japan, further studies that clarify if these types of cases are common in countries other than Japan will also need to be undertaken.

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Changes in urinary uric acid-creatinine ratio after electrically induced convulsions in man. The procedure is then applied to the more complex structures of the bacterial E. c-Jun N-terminal kinase 3 expression in the retina of ocular hypertension mice: a possible target to reduce ganglion cell apoptosis. Thus, many of the features of major depression potentially reflect dysregulations of the stress response.

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Both a disturbance at maturation division and an error at fertilization were the cause of polyploidy. In addition to these primary techniques, a number of experimental palatal training procedures have been reported in the literature. Ras-GRF1 has been implicated as a Ras-specific guanine nucleotide exchange factor (GEF), which mediates calcium- and muscarinic receptor-triggered signals in the brain. A brief explanation and parameter optimization of dithering are given.

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The mean score of the right-hemisphere group fell significantly below that of the left-hemisphere group and normal controls, suggesting that the specialization of the right hemisphere occurs early in development. Using fluorescent proteins to study mRNA trafficking in living cells. Furthermore, using the conditional nature of these transgenic mice, we suggest that receptor expression during the early postnatal period, but not in the adult, is necessary for this behavioural rescue. We propose that the anisotropy and complex phase diagram result from the interplay between strong geometrical frustration and spin-orbit interaction necessary for the description of this fascinating magnetic system. These findings demonstrate that the beta2AR can signal to ERK via a GRK5/6-beta-arrestin-dependent pathway, which is independent of G protein coupling.