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Reeshape (Orlistat)

Reeshape is a carboxylic ester resulting from the formal condensation of the carboxy group of N-formyl-L-leucine with the hydroxy group of (3S,4S)-3-hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2-one. A pancreatic lipase inhibitor, it is used as an anti-obesity drug. It has a role as an EC (triacylglycerol lipase) inhibitor, a bacterial metabolite, an EC (fatty acid synthase) inhibitor and an anti-obesity agent. It is a beta-lactone, a L-leucine derivative, a member of formamides and a carboxylic ester.

Other names for this medication:
Orlistat, Cobese, Ishape, Lipocut, Lipophage, Obelit, Obezita, Oristal, Orlica, Reeshape, Vyfat, Xenical,

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To investigate the prevalence of symptoms and signs related to starvation at the initial examination of adolescent girls with eating disorders (ED). Systematic conservation planning (SCP) is a field of conservation biology concerned with delivering on-the-ground actions that achieve conservation goals. Recent studies have started to explore the scope of ITH in glioblastoma (GBM), a highly aggressive and fatal form of brain tumor, to explain its inevitable therapy resistance and disease relapse. The content of questionnaire included the hygienic and environmental situation, the behavioral characteristics of the residents, and the treatment of schistosomiasis patients. Retraction: Bilateral acute angle closure glaucoma following a snake bite: Are we missing it?

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Swine operations can affect air quality by emissions of odor, volatile organic compounds (VOCs) and other gases, and particulate matter (PM). With a particular focus on parent engagement, this study utilized community-based participatory research to develop and pilot test a family-centered intervention for low-income families with preschool-aged children enrolled in Head Start. Tularemia is a zoonotic disease caused by the Gram-negative intracellular pathogen Francisella tularensis. Effects of antisense p21 (WAF1/CIP1/MDA6) expression on the induction of differentiation and drug-mediated apoptosis in human myeloid leukemia cells (HL-60). Coexistence Of Chronic Lymphocytic Leukemia And Acute Myeloid Leukemia.

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Following administration of the 50 and 100 mg/kg doses, a positive spike (latency of 53 msec) emerged from the middle of a negative wave. Retracted: A randomized clinical study of circumcision with a ring device versus conventional circumcision. For more detailed mapping, we constructed mouse A9 cells containing STFs derived from human chromosome 2 tagged with pSTneo at different regions in 2q31-qter. High LD is seen in populations with a relatively limited and constant size, presumably because of genetic drift.

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The phosphatidylinositol 3-kinase (PI3K) pathway is commonly deregulated in cancer. New type of synthetic peptide library for identifying ligand-binding activity Local Fitting of the Kohn-Sham Density in a Gaussian and Plane Waves Scheme for Large-Scale Density Functional Theory Simulations.

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Clinical observations on ten cases of methanol poisoning with particular reference to ocular manifestations. The ability to more quickly re-establish a normal mechanobiological environment, thus minimizing any catabolic changes, may explain the beneficial effects reported with applied TE in tendinopathy treatment. Serological study with SolcoTrichovac, a vaccine against Trichomonas vaginalis infection in women. The protamine sensors exhibited a stable and reversible response to protamine concentrations ranging from 0.05 to 30 mg L-1.

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Moreover, the levels of IPNV and immune-related gene expression were quantified in fish showing clinical infection as well as in asymptomatic rainbow trout survivors. melanogaster, a prominent model for research on the interaction between nutrition and longevity, dietary restriction is typically based on medium dilution, with possible compensatory ingestion commonly being neglected. We investigated the effect of caffeic acid phenethyl ester (CAPE) on TLR-mediated inflammation and the underlying regulatory mechanism. CT findings in eosinophilic enterocolitis with predominantly serosal and muscular bowel wall infiltration.

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Possible mechanism of disturbances of saccadic eye movements in patients with Parkinson disease To examine whether short- and long-term outcomes after surgery for lumbar stenosis (SPS) and degenerative spondylolisthesis (DS) vary across centers. Color vision may play a role in the control of accommodation and emmetropization. This study was performed to determine the rate of pregnant occupants in motor vehicle accidents (MVA) and the frequency of seatbelt use in pregnancy in Japan.

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Sho-saiko-to increased the apical-to-basolateral transport of tolbutamide, whereas the basolateral-to-apical transport of this drug was reduced by Sho-saiko-to. We suggest that prior thoracoplasty might not necessarily be an exclusion criterion for aortic surgery in cases with adequate pulmonary function.

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In the second part, we describe the use of long and flexible linkers for engineering FRET constructs, including an introduction to a general and efficient tool for making successful fusion proteins with long and flexible linkers. These results indicate that in addition to mediating lymphoid organogenesis, Bcl-3 prevents autoimmune diabetes by inhibiting inflammatory chemokine and cytokine gene transcription.

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Intraluminal NTG at 0.75 mg/kg significantly attenuated the reduction in bile flow that accompanied IR. Polyvalent vaccination against hepatitis B surface and core antigen using a dicistronic expression plasmid.

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The responses of Class 1 neurones to innocuous prodding of their receptive fields were unaffected by neuronal activation in either the lateral or ventrolateral PAG. We find that RSK phosphorylates checkpoint kinase 1 (Chk1) at an inhibitory site, Ser280, both in vitro and in vivo. Compared to rhMPV-WT, rhMPV-Delta G also increased IRF- and NF-kappaB-dependent gene transcription, which was reversely inhibited by G protein expression.

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The sensitivity and accuracy of detection is dependent on the type of probe used, the recording method, the measurement error, and the method of data analysis. Are Vitamin D Drops Containing 400 IU Daily Adequate for Preventing Vitamin D Deficiency? Pharyngeal lymphoid hyperplasia appeared to have little effect on upper airway function.

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Here, we announce the genome sequence of AcaML1 and report major findings from its annotation. Comparative efficiency of feline immunodeficiency virus infection by DNA inoculation. We present a subset of 31 practices applicable to other public health programs and for which differences in how high- and low-performing sites used the practices were identified. Naftopidil inhibits 5-hydroxytryptamine-induced bladder contraction in rats. Thirty Chinese mothers of adult children with moderate to severe mental retardation were interviewed to explore the source and nature of their stress and social support.

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Statin treatment prevents neuroinflammation and blood brain barrier dysfunction in experimental CM and related conditions that are associated with cognitive sequelae, and may be a valuable adjuvant therapeutic agent for prevention of cognitive impairment in patients surviving an episode of CM. The SET7/9 methylation sites in H1.4 were pinpointed to the last lysine residues of the six KAK motifs in the C-terminal domain (K121, K129, K159, K171, K177 and K192).

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Analysis of the resting systolic time interval in hypertensive patients Accurate diagnosis of dentoalveolar ankylosis by assessment of percussion sound and mobility is only possible when more than 20 percent of the root surface is ankylotic. The article concludes that many Pacific public health laws could deliver better support for current health policy, more sensitivity to the culture and customs of the region, and better management of public health risk through laws that are better suited to their Pacific environment, easier to understand, more flexible, and more relevant to current health policy. In 1998, she received the prestigious NHMRC CJ Martin Fellowship and undertook research at the Scripps Research Institute (CA, USA) until 2001. In our experience, the complete protocol in parathyroid scintigraphy increases the accuracy of pre-operative parathyroid localization.

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The structural injuries which lead to this progressive loss of function consist of focal segmental glomerulosclerosis and tubulointerstitial fibrosis and atrophy. Acquired pelvic anomaly preventing sexual intercourse in a female patient.

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Adult attachment interviews (AAI) were rated according to the Reflective Functioning Scale (RF Scale). CR may modify the use of psychiatric services and the patterns of care of patients with schizophrenia. In contrast, when the data were analyzed, inappropriately, as a case-control study, the authors found an OR of 0.55 for probable AD, falsely indicating a protective effect of statins. Notably, ERV activation in immunodeficient mice is prevented in husbandry conditions associated with reduced or absent intestinal microbiota.

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Probably IL-17 is responsible for intensive resorption of bone tissue in rheumatoid arthritis. We tested the hypothesis that the exaggerated sympathetic nerve activity restrains the reflex muscle vasodilatation during exercise in HF patients. To examine the speciation of the 65Zn pool found in this neuronal allopurinol in tumor lysis syndrome definition pathway, we investigated the in vivo incorporation of systemic 65Zn into rat hippocampus compared with other brain regions.

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For this purpose, a scheme for selecting the volume of interest in an oblique plane covering the head, body, and tail of the hippocampal formation (HF) was implemented in a water-suppressed proton chemical shift imaging (CSI) acquisition. It is stressed the importance that has the identification of Candida species causing vaginitis. Influenza vaccination coverage levels in selected sites--United States, 1989. Sixteen cirrhotic patients and dhatrin dosage eight control subjects were included in this study.

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