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Topina (Topiramate)
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Topiramate

Topina is an anticonvulsant medication used in the treatment of epilepsy and migraine headaches. Topina is also commonly used off-label to treat a wide range of mood disorders, eating disorders, and to aid in substance abuse therapy. While Topina's mechanism of action is unclear, we know that the drug blocks sodium channels in the body that deliver electrical impulses to excitable cells (such as nerve, muscle, and brain cells). By doing so, Topina appears to enhance the activity of a chemical messenger (neurotransmitter) known as gamma-aminobutyric acid (GABA).

Other names for this medication:
Topiramate, Topamax, Epitomax, Letop, Neutop, Piramax, Talopam, Topamac, Topictal, Topigen, Topilex, Topimax, Topina, Topiramato, Topirol, Toplep,

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Surgically implanted transmitters measured various metrics of the hibernation phenotype over a 7-day period including changes in motor activity, heart rate and core body temperature. However, information on the physiological function of MLF1 is limited and mostly derived from studies identifying MLF1 interaction partners like CSN3, MLF1IP, MADM, Manp and the 14-3-3 proteins.

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Data were collected using a Vicon 3D motion analysis system and two force platforms. Small nuclear ribonucleoproteins (snRNPs), which are required for pre-mRNA splicing, contain extensively modified snRNA.

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Cerebral malaria in children is associated with long-term cognitive impairment. The antibacterial activities were assessed by measuring the diameter of the inhibition zones, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values. In this paper, we describe the clinical case of a patient with a history of colon cancer and infective endocarditis caused by Streptococcus bovis. In addition, we studied the thymic nurse cell complex, used herein as an in vitro model for ECM-mediated intrathymic T-cell migration.

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We report a very rare metastatic pattern of invasive lobular carcinoma and demonstrate that gross cystic disease fluid protein-15 and mammaglobin are useful in the diagnosis of metastatic breast cancer. The Cuban Medical Association of Cuban expatriate doctors--the case for membership of WMA.

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Therefore, it is important to develop a tool that can measure the quality of clinical education. Retinal bipolar cells were isolated from white bass retinas and maintained in a cell culture preparation.

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The typical decolonization regimen of mupirocin and chlorhexidine bathing is not optimal in burn patients because of chlorhexidine limitations on nonintact skin. As the initial treatment, we carried out transurethral incision of the ureterocele (TUI). Sleep duration and obesity-related risk factors in the rural Midwest. PSM was expressed in all cases of prostate adenocarcinoma, with the greatest extent and intensity observed in the highest grades. Sudden hearing loss in childhood consequent to hepatitis B vaccination: a case report.

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Our aim was to test our hypothesis whether aroma can cure or prevent cancer. Utility of dystrophin and utrophin staining in childhood muscular dystrophy.

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The question arises whether polluting environmental endocrine disrupters may have been responsible. Predicting Health Promotion and Quality of Life With Symptom Clusters and Social Supports Among Older Adults With Multiple Sclerosis.

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Purification and characterisation of an extracellularly released protease of Trypanosoma brucei. The initial rate of decrease in fluorescence is linearly related to enzyme activity. Differences in the regulation of the biosynthesis and esterification of 20- versus 22-carbon polyunsaturated fatty acids. However, attitudes and intended behaviors in 7th graders returned to baseline levels 3 months postpresentation. Substantial density gradients between the denser condyles and the subchondral bone of the sagittal groove were shown to equate with anatomical differences in loading intensity during locomotion.

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Previous studies have identified a minimal 434 bp enhancer from the promoter region of the Ciona Brachyury gene (Ci-Bra), which is sufficient to direct a notochord-specific pattern of gene expression. The primary efficacy parameter was incidence of cardiovascular events for amlodipine vs placebo. Periods of high ED crowding were associated with increased inpatient mortality and modest increases in length of stay and costs for admitted patients. Metastatic renal carcinoma presenting with profuse haemorrhage at cardiac surgery. Prevention and control of chronic non-communicable diseases in Spain: A call to action

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An emerging trend in this direction is Theranostics which represents a combinatorial diagnosis and therapeutic approach to cancer disease and aims to eliminate multi-step procedures, reduce delays in treatment and improves patient care. Many clinical guidelines have adopted a multifactorial cardiovascular risk assessment to identify high-risk individuals for treatment.

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From measurements at two gaps with smooth surfaces, we use two slip correction methods and check their validity by a direct comparison with actual measurements (with grooved surfaces). Simple and rapid urine concentration procedure for protein electrophoresis. Clear cell and papillary serous endometrial carcinomas: survival in a series of 128 cases. This leads to the downregulation of c-Myc transcriptional target miR-17-92 cluster, whose expression has a well-defined role in contributing to block monocytic differentiation and sustain AML cell proliferation. Studies suggest that cortisol response to stress has a strong genetic etiology, and that FK506 binding protein 5 (FKBP5) and G-protein coupled type-I CRH receptor (CRHR1) are key proteins regulating response.

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Results demonstrate the promise of mentalization-based interventions provided concomitant with addiction treatment for mothers and their young children. Recent reports demonstrated the increased motility of human mesenchymal stem cells (hMSC) grown under hypoxic conditions compared to normoxic cells.

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Since low-level laser therapy (LLLT) modulates inflammatory responses, and promotes pain reduction and cellular biostimulation, LLLT can be suggested as an alternative treatment for RAUs. Is there a role for physician assistants in community mental health? The sudden displacement of the bladder wall against the cutting loop may cause a perforation of the bladder.

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Attitude and behavior related to organ donation and affecting factors: a study of last-term students at a university. The effect of inducer polarity and contrast on the perception of illusory figures. The aim of this study was to establish whether such diurnal rhythms are also present in healthy humans. There were also substantial gender differences in smoking relations to intake, with male smokers tending to have higher overall and meal intakes particularly of fats than non-smokers, whereas female smokers tended to have lower overall intakes, fewer meals, and lower amounts of carbohydrates than non-smokers.

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Few studies have examined how levels of activity intensity fluctuate throughout later life in older adults and no study has identified correlates of sustained activity levels in this age group. Meanwhile, according to all the tests performed, the other O-PS in every strain is immunochemically homogeneous and identical to one of the determinants revealed in the more diversified O-PS. Modifications of the connective tissue of the albuginea of normal human testicle at various ages

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We next discriminated 1,799 enhancers unique to islets and showed that these islet-specific enhancers have reduced association with annotated genes, and identified a subset that are instead associated with novel islet-specific long non-coding RNAs (lncRNAs). These results are consistent with a model whereby PV and HRV disrupt nucleo-cytoplasmic trafficking by selectively removing FG repeat domains from a subset of nuclear pore complex proteins. Laparoscopic sleeve gastrectomy (LSG) is an innovative and relatively safe surgical approach for weight reduction in morbidly obese people. In vivo experiments demonstrated that inhaled DPI system of CsA attenuated inflammatory events in experimental asthma/chronic obstructive pulmonary disease (COPD) model rats as evidenced by a decrease of infiltrated granulocytes, and there was no excessive increase in systemic exposure of CsA at a pharmacologically effective dose, possibly leading to reduced systemic side effects.

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This study investigated whether the neighborhood tobacco retail environment was associated with individual-level smoking and cessation in Scottish adults, and whether inequalities in smoking status were related to tobacco retailing. Heparin-stimulated modification of C1-inhibitor by subcomponent C1s of human complement. Analysis of the results suggests two causes for the apparent instability of the remainder of the structures inside the lipid bilayer, both resulting from the desolvation of channel polar groups (i.e.

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Our findings indicate that a novel association in the MSRA gene is related to oxidative stress and support the notion of a major role for this process in RA. Isoniazid was condensed with cinnamic aldehyde after trichloroacetic acid deproteinisation. Sporocytophaga is a kind of bacteria that can glide on the solid medium surface. Clinical results in children with the sulfonamide mixture dosulfin

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The use of in situ and ex situ techniques for the study of the formation mechanism of mesoporous silica formed with non-ionic triblock copolymers. Adult adrenocortical carcinoma has a poor prognosis, underscoring the importance of identifying diagnostic and prognostic markers. Impaired lipolysis was not due to reduced pancreatic lipase secretion.

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In randomized controlled trials consumption of low calorie sweeteners have accompanied with lower intake of sugar containing food, higher healthy eating index and better weight management. Structure of the chemokine receptor CXCR1 in phospholipid bilayers. Thus, recent randomised trials showed that a replacement therapy with long course of low dose corticosteroids reduced mortality from septic shock.

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This study investigated whether kinship effects on social interactions vary depending on the species dominance style. Performance improvements were noted after wearing the Vayu Vest, potentially because of changes in arousal. The main ingredient in this calculation are correlations between scattering trajectories which are due to trajectories that approach the trapped periodic orbits closely. Suspension of the lens is complex and sophisticated in teleosts (bony fishes) and tetrapods.

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Shoulder kinematics in patients with full-thickness rotator cuff tears after a subacromial injection. Avalanche segregation, stratification and also segregation in rotating drums are examined.

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Strict infection control measures are essential to prevent nosocomial transmission. Thioredoxin is a redox active protein which has been implicated in reproductive processes. We propose that phospholipid transfer protein activity becomes reduced under cholestasis conditions because of changes in the chemical composition of high density lipoproteins, such as an increase in phospholipids content.

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Meta-analysis of Dengzhanxixin injection treatment for unstable angina pectoris The cytoplasmic NPM mutant not only affords protection from death ligand-induced cell death but also suppresses caspase-6/-8-mediated myeloid differentiation. Learning impairment in mice following acute exposure to dichloromethane and carbon tetrachloride. To study the correlation between right (RE) and left eye (LE) keratometry readings (K) and axial lengths (AL) in a population-based sample of normal subjects.

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Enhancement of PFC DA signaling with tolcapone improves both PPI and working memory in a COMT Val158Met genotype-specific manner. To date, the uptake of chlamydia screening in community pharmacies has been limited. pLTR-DT entrapped by the cationic TMAG-liposome was not digested by the treatment with DNase I and with serum. Fifteen healthy volunteers underwent two forms of movement intervention in two consecutive days in a counter-balanced manner. Spontaneous contractions and those elicited by two different methods of electrical stimulation were studied in isolated segments of bovine mesenteric lymphatic vessels.

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Application of PCR test to clinical samples of aspergillosis patients is discussed. Xenon-enhanced DECT is safely feasible and can add relevant diagnostic information in mechanically ventilated intensive care patients with worsening respiratory function. It is proposed that this difference is dependent on the origin of appropriate irradiations. Cloned murine fetuses produced by nuclear transfer using metaphase-arrested embryonic stem cells.

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Variations of alkaline phosphatase in cerebrospinal fluid in tuberculous meningitis For the next future, these may include the transfer of specific T-cells and other immunotherapeutic approaches.

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A novel syndrome of cerebral cavernous malformation and Greig cephalopolysyndactyly. Generated reporter gene cell lines fully maintained responsiveness to glucocorticoids for 32 days in the culture and over 16 passages without significant alterations.

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However, to extract the large cohorts necessary for genome-wide association studies, natural language processing methods to process narrative text data may be needed. Isolates of brain tissue from the BSE case in Alberta, 3 farmed elk with chronic wasting disease (CWD) from different parts of Saskatchewan, and 1 farmed white-tailed deer with CWD from Edmonton, Alberta, were examined alongside isolates of brain tissue from BSE, ovine scrapie, and sheep experimentally infected with BSE from the United Kingdom (UK). Despite the increase in social security affiliates in the studied period, the incidence of PD was fairly stable during this period, with a decline between 1997 and 2000, which could be attributed to measures of evaluation and monitoring of IP adopted in 1995.

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The guidelines presented have been devised to equip practitioners to fulfil their professional role as defined in a previous study, by identifying objectives, educational pathways, and means of assessment. Each member of the pharmacokinetics service is credentialed by the medical staff.

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Small doses of methadone, phencyclidine, chlordiazepoxide and pentobarbital increased rates of responding under the fixed-interval component of the schedule. Registration of central paths and colonic polyps between supine and prone scans in computed tomography colonography: pilot study. By using an orthogonal partial least squares (OPLS) model, subtle fold-changes were accurately measured in the urine samples spiked with (13)C and (15)N isotope labelled amino acids at different concentrations.

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Effects of electron-cyclotron-resonance-heating-induced internal kink mode on the toroidal rotation in the KSTAR Tokamak. Role of Nad(P)h: quinone oxidoreductase in the regulation of intracellular redox state.

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Binding of the TATA-binding protein (TBP) to the promoter is a pivotal step in RNA polymerase II transcription. The high odds ratio and high specificity of the detected genetic combinations allow one to hope that they will be clinically used as predictors. The addition of a non-radioactive in situ hybridisation assay for H19 RNA to the panel of tumour markers used for the histopathological and cytological diagnosis of hepatocellular carcinoma might be useful.

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Termination of early pregnancy with antiprogestin and prostaglandin Molecular biomarkers associated with premature AGA were identified through gene expression analysis using cDNA generated from scalp vertex biopsies of hairless or bald men with premature AGA, and healthy volunteers.

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vulgaris induced slight, but significant transformation of equine peripheral blood lymphocytes. Radiologists need to recognize the clinicoradiologic characteristics to differentiate pseudolesions from true residual or recurrent HCC. Spatial delayed alternation of rats in a T-maze: effects of neurotoxic lesions of the medial prefrontal cortex and of T-maze rotations.

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Development of a waxy gene real-time PCR assay for the quantification of sorghum waxy grain in mixed cereal products. The hatching rate tended to decrease, and nauplius mortality rate to increase, with increased CO(2) concentration. Both oxygenated fatty acid derivatives were activated to the corresponding CoA esters and subsequently metabolized to compounds of shorter chain length.

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Root nodule symbiosis is activated by rhizobial signalling molecules, called Nodulation factors (NFs). Mathematical modeling of MSW combustion and SNCR in a full-scale municipal incinerator and effects of grate speed and oxygen-enriched atmospheres on operating conditions. Our results demonstrate contingent involuntary motoric inhibition: motoric inhibition can be automatically triggered by a stimulus based on top-down goals. Purification and partial characterization of the glutathione S-transferase of rat erythrocytes.

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Disparities in CRC outcomes for urban underserved populations persist. Partnership with a local nursing school is critical to enhance sustainability of the intervention. Revisions of respective care plans are advocated with more realistic outcome expectations and specific actions for the respective case-mix groups.

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Many psychosocial interventions have however been conceptualized in high income countries and seropram gouttes effects secondaires du assessing their feasibility and acceptability in low and middle income countries is pertinent and the objective of this review. The EMT-paramedic: a profile of voluntary medical paraprofessionals. Micafungin (MCFG), recently licensed in Japan, is an active agent for both Candida and Aspergillus.

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In this study, altered laboratory parameters during the course of naturally acquired acute, subacute and chronic bovine besnoitiosis are described for the first time. Although glucose is the main source of energy for the human brain, ketones play an important role during starvation or injury. Given the fact terazosin hcl drug interactions that the superiority of a prosthesis cannot be proven and the cost of the implant is greater, we recommend the trapeziectomy with ligament reconstruction and tendon interposition as opposed to arthroplasty as the first choice in the treatment of basal joint osteoarthritis of the thumb. Given the known burden of mental health disorders among student populations, it is important universities consider effective strategies to address mental health issues. Included were patients with CMV retinitis lesions at least 750 microm outside of zone 1.

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Fine needle aspiration of pleomorphic adenoma and adenoid cystic carcinoma spironolactone for treatment of hair loss of salivary gland origin. Local recurrence developed in 10 patients, regional metastases in 9, and widespread dissemination in 12.

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Based on sound anatomical and biomechanical considerations, anecdotal experience, and available research, however, treatment strategies for pronator syndrome and anterior interosseous nerve syndrome compression neuropathies can be divided into 4 major categories: (1) rest/immobilization, (2) modalities, (3) nerve gliding, and (4) nonconservative treatment. In our study, by using both the Phase II HapMap data and the disease variants extracted from OMIM, a gene-centric evaluation was first metronidazole iv dosis perros chihuahua performed to evaluate the ability of the approaches in capturing the disease variants in Caucasian population. However, leishmaniasis is only transmitted by blood-feeding sandflies, not through human remains. A systematic approach aimed at addressing the underlying abnormalities was developed. While the radiological presentation of FOD in this series of Chinese women appeared similar to that reported in Western populations of Negroid origin, the greater prevalence of symptoms in the former may arise from secondary infection of the FOD lesions due, until recently, to the lack of availability of formal dental care.

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Evaluation of the biocompatibility of a new vascular prosthesis coating by detection of prosthesis-specific antibodies. The present study is an attempt to utilize hybrids among several inbred strains of rats as useful animals for the studies of effectiveness and toxicology on aviral jain american appraisal canada drugs., Four-way crosses were made among the LEW, WM, F344 and DRY strains of rats, and their characteristics were examined. Function of lipid droplet-organelle interactions in lipid homeostasis.

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Creatinine and creatinine-d(3) were monitored using precursor and product ion settings (m/z 114 to 86 and m/z 117 to 89, respectively). In cancer cells stafcure inj they converge oxidative stress signaling to cell cycle arrest and cell death or promote a motile phenotype. The patient was alive and well with no evidence of disease at 15 months after the surgery without any additional therapy. The fillings inserted during the same treatment period as the radiographs had been taken were then grouped on the basis of the scores. The application of peptide and peptidomimetic chiral selectors in LC is reviewed in this article.

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The need for data harmonization--a response guignol de l info omeprazole to Boden and Ozonoff. Recent studies have indicated stabilization in the incidence rates of renal replacement therapy (RRT) for end-stage renal disease (ESRD) in a number of European countries, the USA, and Japan.

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Stereoselective metabolism of 7-nitrobenz(a)anthracene to 3,4- and 8,9- trans-dihydrodiols. We report here a case of recurrent intrabiliary tumor thrombi due to hepatocellular carcinoma, successfully treated by cholangioscopic ethanol injection in which the intrabiliary tumor thrombi were completely eliminated. He had chronic constipation and had taken aspirin for about 10 years thiopental maintenance dose of valacyclovir because of a previous brain infarction.