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GWA analysis for milk production traits in dairy sheep and genetic support for a QTN influencing milk protein percentage in the LALBA gene. The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA. The crystal structures of two human TCRs specific for a HTLV-I Tax peptide bound to HLA-A2 were recently determined, for the first time allowing a functional comparison of TCRs for which the MHC/peptide/TCR structures are known.

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TSP1, via CD47, inhibits eNOS activation and endothelial-dependent arterial relaxation and limits ACh-driven decreases in blood pressure. Stricture disease continues to be a significant complication of hypospadias reconstruction. The patient made an uneventful recovery and was fully continent after surgery. Other important descriptors were V followed by P, both of which exhibited a positive correlation with adsorption, indicating that their size and polarizability favors adsorption.

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One instance is the homology between a peptide of mycobacterial Hsp65 and the myelin protein CNP. Partial cicatricial stenosis of the hypopharynx: report of a case. The decrease of VAS scores seen at the first 2 weeks continued steadily up to the end of 12th week.

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For a model of given type, the independence model, the first-order Markov chain and the hidden Markov model (HMM), we derive the uniform lower bound for the rate of decay for the errors of the maximum likelihood (ML) estimates of the model parameters and, subsequently, the uniform confidence intervals for the parameters. ATD significantly decreased plasma tryptophan (67.0 (2.0) v 24.9 (2.0) mumol/l) and 5-hydroxyindole acetic acid concentrations (29.9 (1.0) v 15.8 (0.6) nmol/l). Physiopathological considerations on the oscillographic and plethysmographic behavior of the peripheral circulation in patients with cranial injuries There were no significant age-related changes in the area positive for HRP-TMB reaction products in rostral and caudal portions of the cortices and the hippocampus of SAMR1. Children and young adults demonstrate low trabecular vBMD, cortical structure and muscle area following Fontan.

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We evaluated 8 children with bladder-prostate rhabdomyosarcoma treated at our institution between 1999 and 2003 according to inclusion criteria. MATRICS consensus cognitive battery--standard for the assessment of cognitive functions in clinical trials in schizophrenia

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Mechanisms underlying hematopoietic stem cell mobilization induced by the CXC chemokine interleukin-8. Furthermore, the mechanism behind this relationship has not been empirically tested.

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To explain the relationship between a positive nurse practice environment (NPE) and implementation of evidence-based practices. Dopamine receptor subtypes have been classified generally as D1-like (e.g., D1, D5) or D2-like (D2, D3, D4), and converging evidence suggests that D2-like receptors may be especially important in mediating the abuse-related effects of cocaine. Criteria for enrollment, recruitment strategies, demographic information, and zygosity assignment are explained for each sample.

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We bring together three approaches, applying two objective tasks (local target analysis and global target location) to two scenarios, together with subjective quality ratings and three computational metrics. Distinct sets of corticosteroid-unresponsive genes modulate disease severity in asthma. There is no basis for advising women with PXE to avoid becoming pregnant, and most pregnancies in PXE are uncomplicated. The spiritual topics that arise from this study offer caregivers a framework for signalling the spiritual needs of patients.

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Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development. Elucidation of the hepatic hemodynamics in acute ethanol administration is an issue of clinical importance for better understanding of alcoholic liver diseases. Audiological outcome after vibroplasty depends on the coupling efficiency reflected by the vibroplasty threshold. The computer aided underwriting procedure means a substantial progress compared to the classical method. A technique utilizing visuoscopy and an afterimage has been performed on somewhat less cooperative patients.

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These results offer novel insights in our pathogenetic understanding of the disease and propose AQP1 as potential therapeutic in vivo target. In this study, the effects of safranal, on blood pressure of normotensive and desoxycorticosterone acetate (DOCA) - salt induced hypertensive rats in chronic administration were investigated. In the present study, by using the more sensitive reverse transcriptase-polymerase chain reaction with a specific set of primers for each isoform and Southern blot analysis, we found that both isoforms of the GABA(B) receptor are expressed not only throughout the brain but also in all peripheral organs examined, including heart, spleen, lung, liver, small intestine, large intestine, kidney, stomach, adrenal, testis, ovary and urinary bladder.

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The data reduction and categorization process developed by TEDDY enables analysis of single infectious agents as well as larger arrays of infectious agents or clinical disease entities. However, among these drugs, isoniazid and rifampicin, especially when administered intermittently, may very rarely be linked to acute autoimmune haemolytic anaemia. Diabetes mellitus is a complex metabolic disorder accompanied by alterations in cellular physiology, metabolism, and gene expression. We have used DNA recombinant technologies to examine the genome of normal and neoplastic tissues from 12 different patients with such tumors.

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Histological examination of a biopsy of the mass showed a fibroadenoma. The SPRY domain has been identified as a subdomain within the B30.2-like domain.

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Unenhanced MRA using SLEEK was performed on a 1.5-T MRI system for assessing renal arteries in 50 patients with hypertension. Correlates of family burden under medicaid managed mental health care. Positive reactions of the epidermis and intestinal mucosa with these mAbs were induced by cutaneous or intestinal infections with parasites.

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However, we describe a method by which the relationship between acceleration metrics and speed can be corrected ad hoc, until tracks accord with periodic ground truthed positions, obtained via a secondary means (e.g. This pertains especially to cases of disturbances in bone union (delayed union, non-union). Studying regulatory T cells in kidney allograft acceptance versus chronic rejection may help in the understanding of more mechanisms of immune tolerance and, in the future, may enable clinicians to induce immune tolerance and decrease the use of immunosuppressive drugs. The doped NW arrays could be the basis for building integrated nanoscale transistors, sensors, and photodetectors.

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Maximum EFT was measured at end-systole on the midventricular free wall of the right ventricle. Using Medline, Psychinfo and reference lists from relevant publications, articles were identified testing pen-and-paper screens in the primary care population aged over 60 years.

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Quinapril produced beneficial hemodynamic effects similar to that observed in the normotensive rat model. Analytical methodologies for evaluating the volatile fraction and the sensory properties of virgin olive oils are elucidated. Bone age and probable aetiological causes in primary nocturnal enuresis. Descending division of the brachium conjunctivum in the cat a cerebello-reticular system. Measles reimmunization may not be effective in protecting HIV-infected children.

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A search string was used to search 2 English aggregator databases, ProQuest and EBSCOhost, on 12 March 2015. These antibodies, which were designated POM2 and POM12, recognise type 1, but not type 2, PrP(Sc). Long-term studies of 2 (cytohistology and genetic monitoring) laboratories of the Research Institute of Human Ecology and Environmental Hygiene, Russian Academy of Medical Sciences, to investigate the influence of environmental factors in the experiments made it possible to develop a noninvasive procedure for evaluating their cytological and cytogenetic impacts on man. Their general health problems include large families, substandard housing, overcrowding, lack of piped water supply and sanitary excreta disposal, malnutrition and prevalent diseases such as cholera, typhoid, dysentery and parasitic infections.

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The relationship between diet and breast cancer in men (United States). The alterations in pituitary hormone mRNA levels with sustained critical illness are compatible with altered hypothalamic and peripheral regulation of pituitary hormone release as previously suggested indirectly by responses to exogenous releasing factors. The patient is 6 months after completion of treatment and is free of disease. Conventional tests for hepatic function such as serum transaminases and alkaline phosphatase do not often reflect simultaneously histopathologic changes of the liver. Carcinogenicity study of tetramethylthiuram disulfide (thiram) in F344 rats.

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Fossil fuel consumption will probably need to be reduced below a quarter of primary energy supply by 2100 and the allowable consumption rate drops even further if negative emissions technologies remain technologically or economically unfeasible at the global scale. Effectiveness of border screening for detecting influenza in arriving airline travelers. Mutation of all Runx (AML1/core) sites in the enhancer of T-lymphomagenic SL3-3 murine leukemia virus unmasks a significant potential for myeloid leukemia induction and favors enhancer evolution toward induction of other disease patterns. To describe the changes in pulmonary function tests (PFTs) and computed tomographic imaging of the thorax over a 15 year period after cessation of exposure to asbestos in a cohort of Israeli power plant workers.

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Small mammalian wound healing models are the most popular animal models for wound healing research because they are inexpensive, readily obtainable, and easy to handle. In the near future, clinical trials will determine whether MRD assessment can be used for guiding therapy, either to improve quality of responses through consolidation or to prevent relapses through preemptive therapies based on the reappearance of MRD. Characterization of fat metabolism in the fatty liver caused by a high-fat, low-carbohydrate diet: A study under equal energy conditions. The distribution of oxytetracycline hydrochloride in two batches of 4,000 kg of pig-rearing pellets (400 ppm) was studied.

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N1,N11-diethylnorspermine (DENSPM) or alpha-difluoromethylornithine (DFMO), have synergistic effects in killing HCT116 colon carcinoma cells with wild-type or absent p53. Biological and psychological correlates of self-reported and objective sleep measures.

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The present study was designed to evaluate the role that central gamma-aminobutyric acid type B (GABA-B) receptor plays in neutrophil migration in a murine model of zymosan-induced arthritis by using different pharmacological tools. Leiomyosarcomas are rare tumours, predominantly localized in the stomach, small intestine and retroperitoneum. In fall 2014, a one-semester crossover course called Hacking Healthcare was developed by the University of Amsterdam in cooperation with the Gerrit Rietveld Academie of Fine Arts and six health care institutions in the greater Amsterdam area.

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The axonal staining is transient, disappearing during the second postnatal week of development. National Institutes of Health Consensus Development Conference Statement. Also, the mean preoperative KOSA-18 scores of the small, moderate, and large impact groups were significantly improved both at postoperative 1 month and 6 months. It takes into account that cells are able to convert only part of the energy absorbed. Cells of the macrophage lineage take up large amounts of parenterally administered liposomal material.

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Subjects underwent driving simulator testing at 1 am on 2 nights a week apart. Point-of-care tests for the diagnosis of Neisseria gonorrhoeae infection: a systematic review of operational and performance characteristics. Three major types of papillae have been observed: filiform, conical, and vallate.

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miR-20b is up-regulated in brain metastases from primary breast cancers. Lower serum albumin is a strong independent predictor for VTE events in NS.

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To develop an HPLC method for determining oxyphyllenodiol A (1) and teuhetenone A (2) contained in Alpinia oxyphylla and to compare the contents of the two components contained in medicinal materials and prepared herbal medicines in pieces sold in the market and different fractions. Using a radioimmunoassay to determine juvenile hormone (JH) titers as well as in vitro JH biosynthesis, we observed that retention of mature follicles in egg-retaining females, i.e., virgins or mated females not provided an egg-laying substrate, inhibits JH production and consequently oocyte development. Age trajectories of mortality from all diseases in five countries of central Europe during the last decades. The aims of this study were (1) to reexamine the efficacy and safety of higher doses of vitamin B(6) versus placebo in a greater sample of patients for a longer time and (2) to evaluate the carryover effect of vitamin B(6).

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We also examined the sensitivity of these striatal signals to the value associated with social group membership. Left ventricular shortening fraction decreased significantly in five other children during induction. Action of elastase on fibrinolysis activated with streptokinase. Determination of Senecio alkaloids by thermospray liquid chromatography/mass spectrometry. The result of macronuclear transplantation demonstrated that autogamy was under the control of macronucleus.

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NPDS was done on a 32-year-old male unilateral open-angle glaucoma secondary to idiopathic dilated episcleral veins. Ivor-Lewis esophagectomy is associated with significant postoperative analgesic requirements and perioperative complications. Explanatory and pragmatic estimates of the treatment effect when deviations from allocated treatment occur.

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Effect of luteolin and apigenin on rosmarinic acid bioavailability in Caco-2 cell monolayers. Effects of local tetanus on the potassium liberation from skeletal muscles by acetylcholine There was greater loss in the maxilla than mandible with fixed complete dentures and overdentures, whereas little arch difference was noted with fixed partial dentures. This behavior was confirmed by the allometric relationships found between changes in the root length with (15)N and water accumulation in the shoot. The relative capacity of these monoamines to generate H2O2 and to incorporate iodine into tyrosine has also been studied.

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Eggs were sought in the oviducts and ciliary activity in the fimbrial and ampullary sections of the oviducts was determined by light microscopy, before detailed examination by scanning electron microscopy. Single neuronal responses in medial prefrontal cortex during cocaine self-administration in freely moving rats.

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There is no universal consensus on the treatment of this disease. Toxicant-induced leakage of germ cell-specific proteins from seminiferous tubules in the rat: relationship to blood-testis barrier integrity and prospects for biomonitoring.

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We found that Tabebuia inhibited dose dependent ConA stimulated T-cell proliferation. Specific choice of the working wave length during analysis of somatic muscle fibers using a biwave photometry method Porcine reproductive and respiratory syndrome virus (PRRSV) is a major pathogen of swine worldwide. In addition, apparent intrinsic mobility of some of the tertiary cysts implying viability was detected only by 3DTTE.

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Isolation of immediate-early differentiation mRNAs by enzymatic amplification of subtracted cDNA from human endothelial cells. We conclude that the B-subunit induces lipid reorganization that favours negative membrane curvature, which drives the formation of inward membrane tubules. New aspects of the clarification of non-anamnestic sero-positive cases of syphilis, with special regard to cardiolipin reactions The synthesis, characterization, and structure-guided application of a new class of highly versatile chiral C(2)-symmetric diamine-oligothiophene ligands in Pd-catalyzed asymmetric transformations are presented. Mechanisms of daptomycin resistance in Staphylococcus aureus: role of the cell membrane and cell wall.

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This was an observational, cross-sectional study of 300 consecutive adult patients receiving ambulatory anti-cancer treatment at an Australian tertiary hospital. Thirty-eight children returned for reevaluation 6 to 13 years (average 9.5 years) after entry. Safety and efficacy of a Ventralight ST echo ps implant for a laparoscopic ventral hernia repair - a prospective cohort study with a one-year follow-up. Although it is a limited, single case report, it provides insight into the potential for this combination and may serve as a stimulus for a large, well-controlled study to evaluate the use of toxins in this and similar areas. It remained undetermined, which pathogen played the central role in the AE pathogenesis.